SCHEMBL472281

SCHEMBL472281

CN(C)c1ccc(CCC(=O)O)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 11/20 0.59
KEAP1 Q14145 1/20 0.57
ALDH1A1 P00352 3/20 0.50
MAPK1 P28482 2/20 0.50
MAPT P10636 2/20 0.50
FFAR4 Q5NUL3 2/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
LMNA P02545 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
NPC1 O15118 1/20 0.50
ALOX15 P16050 1/20 0.50
NFKB1 P19838 1/20 0.50
RAB9A P51151 1/20 0.50
NFKB2 Q00653 1/20 0.50
RELA Q04206 1/20 0.50
MCL1 Q07820 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
CYP3A4 P08684 1/20 0.50
TSHR P16473 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472311 0.89 ALDH1A1 (0.61) FFAR1ALDH1A1MAPK1MAPTLMNA
SCHEMBL28008810 0.86 ALDH1A1 (0.52) ALDH1A1MAPK1MAPTL3MBTL1NPC1
SCHEMBL8136098 0.84 ALDH1A1 (0.59) ALDH1A1MAPK1MAPTLMNANPC1
SCHEMBL5593599 0.83 CYP1A2 (0.51) FFAR1KEAP1ALDH1A1MAPTFFAR4
SCHEMBL69746 0.82 FFAR1 (0.81) FFAR1KEAP1MAPK1FFAR4CA1
SCHEMBL27278134 0.82 ALDH1A1 (0.49) ALDH1A1MAPK1MAPTCA1CA2
SCHEMBL1469760 0.82 ALDH1A1 (0.46) FFAR1ALDH1A1MAPK1MAPTNPC1
SCHEMBL14732640 0.82 FFAR1 (0.67) FFAR1KEAP1ALDH1A1MAPTFFAR4
Hydrochloric Acid SCHEMBL25264643 0.80 FFAR1 (0.77) FFAR1KEAP1MAPK1FFAR4CA1
SCHEMBL14610940 0.80 FFAR1 (0.59) FFAR1KEAP1ALDH1A1FFAR4CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0022188-B1 CO-INITIATOR COMPOSITIONS FOR PHOTOPOLYMERIZATION CONTAINING 3-ACYL-SUBSTITUTED COUMARINS, PHOTOPOLYMERIZABLE COMPOSITION AND PHOTOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-03 EP claimed
CN-115215756-B Organic fluorescent probe with endoplasmic reticulum targeting function, and preparation method and application thereof 华南理工大学 2023-10-27 CN disclosed
CN-115215756-A Organic fluorescent probe with endoplasmic reticulum targeting function and preparation method and application thereof 华南理工大学 2022-10-21 CN disclosed
EP-2492746-B1 Chemically amplified negative resist composition and patterning process SHINETSU CHEMICAL CO (JP) 2019-11-20 EP disclosed
CN-105607426-B Polymer, chemical amplification negative resist composition and pattern forming method SHIN ETSU CHEMICAL COMPANY (JP) 2019-11-01 CN disclosed
EP-2492747-B1 Chemically amplified negative resist composition and patterning process SHINETSU CHEMICAL CO (JP) 2018-11-07 EP disclosed
EP-2270596-B1 Positive resist compostion and pattern forming process SHINETSU CHEMICAL CO (JP) 2018-07-25 EP disclosed
CN-104330955-B For the chemical-amplification positive anti-corrosion agent composition and patterning method of EB or EUV lithographic printings 信越化学工业株式会社 2018-05-25 CN disclosed
US-RE46765-E1 Chemically amplified negative resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-03-27 US disclosed
US-RE46736-E1 Chemically amplified negative resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-02-27 US disclosed
EP-1104420-B1 SUBSTITUTED 1,8-NAPHTHYRIDIN-4(1H)-ONES AS PHOSPHODIESTERASE 4 INHIBITORS PFIZER PROD INC (US) 2002-12-18 EP disclosed
CN-1312810-A Substituted 1,8-naphthyridin-4(1H)-ones as phosphodiesterase 4 inhibitors PFIZER PROD INC (US) 2001-09-12 CN disclosed
EP-1104420-A1 SUBSTITUTED 1,8-NAPHTHYRIDIN-4(1H)-ONES AS PHOSPHODIESTERASE 4 INHIBITORS Pfizer Products Inc. (US) 2001-06-06 EP disclosed
US-6174895-B1 USEFUL IN TREATMENT OF RESPIRATORY, ALLERGIC, RHEUMATOID, BODY WEIGHT REGULATION, INFLAMMATORY AND CENTRAL NERVOUS SYSTEM DISORDERS SUCH AS ASTHMA, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, ADULT RESPIRATORY DISEASES SYNDROME, FIBROSIS PFIZER INC. 2001-01-16 US disclosed
US-6069149-A ANTIALLERGENS, ANTIINFLAMMATORY AGENTS TERUMO KABUSHIKI KAISHA (JP) 2000-05-30 US disclosed
WO-2000009504-A1 SUBSTITUTED 1,8-NAPHTHYRIDIN-4(1H)-ONES AS PHOSPHODIESTERASE 4 INHIBITORS PFIZER PRODUCTS INC. (US) 2000-02-24 WO disclosed
EP-0894797-A1 NOVEL AMIDE DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF TERUMO KABUSHIKI KAISHA (JP) 1999-02-03 EP disclosed
US-5414108-A From a Meldrum's acid derivative BIOGAL GYOGYSZERGRAR (HU) 1995-05-09 US disclosed
US-5350872-A Decyclization and decarboxylation of a 1,3-dioxane-4,6-dione BIOGAL GYOGYSZERGRAR (HU) 1994-09-27 US disclosed
EP-0578850-A1 Process for the preparation of carboxylic acids and derivatives of them BIOGAL GYOGYSZERGYAR (HU) 1994-01-19 EP disclosed