Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | KMO | O15229 | 2/20 | 0.46 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3929582 | 0.99 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL3922934 | 0.97 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL3922928 | 0.86 | ALDH1A1 (0.52) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL1457799 | 0.85 | HDAC1 (0.57) | ALDH1A1KDM4ELMNARAB9ANPC1 | |
| SCHEMBL3922955 | 0.84 | RAB9A (0.55) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL5905796 | 0.81 | ALDH1A1 (0.51) | ALDH1A1KDM4ELMNAKMT2ARAB9A | |
| SCHEMBL25312971 | 0.78 | KDM4E (0.71) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL29466392 | 0.78 | KDM4E (0.71) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL18544548 | 0.77 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNAMAPTKMT2A | |
| SCHEMBL6391701 | 0.76 | RAB9A (0.69) | ALDH1A1KDM4ELMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7563797-B2 | Substituted imidazo(1,2-A)pyrimidines and imidazo(1,2-A) pyridines as cannabinoid receptor ligands | Forest Laboratories Holding Limited (BM) | 2009-07-21 | — | — | US | disclosed |
| WO-2008027812-A2 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-03-06 | — | — | WO | disclosed |
| US-20080058350-A1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE DERIVATIVES | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2008-03-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080058350-A1 | IMIDAZOPYRIDINE AND IMIDAZOPYRIMIDINE DERIVATIVES | CNR2, CNR1, P2RY4 | ALDH1A1 3141/4885KDM4E 1477/4885LMNA 4165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.