Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL235061 | 0.98 | MAPT (0.50) | LMNAALDH1A1MAPTKDM4EMEN1 | |
| Ammonia Solution, Strong SCHEMBL28289433 | 0.95 | MAPT (0.48) | LMNAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL18572064 | 0.91 | LMNA (0.51) | LMNAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8324832 | 0.86 | TSHR (0.50) | LMNAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL769551 | 0.85 | CA12 (0.50) | LMNAALDH1A1MAPTCA12CA2 | |
| SCHEMBL14029335 | 0.85 | LMNA (0.43) | LMNAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL8591158 | 0.84 | CA12 (0.41) | LMNAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL23509359 | 0.84 | ALDH1A1 (0.51) | LMNAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL14029328 | 0.84 | MEN1 (0.48) | LMNAALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL20084554 | 0.84 | LMNA (0.47) | LMNAALDH1A1MAPTKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7572837-B2 | Process for the production of flexible polyurethane foams | TOSOH CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20030144371-A1 | Catalyzing the copolymerization in presence of imidazole compounds, free of tin comound, forming polyetherurethane copolymers | TOSOH CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1312630-A1 | Process for the production of flexible polyurethane foams | Tosoh Corporation (JP) | 2003-05-21 | — | — | EP | disclosed |