Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 4/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2425206 | 0.91 | DGAT1 (0.39) | DGAT1ALOX5APFEN1 | |
| SCHEMBL2423940 | 0.88 | DGAT1 (0.40) | DGAT1ALOX5APFEN1 | |
| SCHEMBL3929309 | 0.85 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL2429523 | 0.83 | DGAT1 (0.35) | DGAT1 | |
| SCHEMBL2425986 | 0.82 | DGAT1 (0.38) | DGAT1ALOX5APFEN1 | |
| SCHEMBL2425401 | 0.81 | DGAT1 (0.38) | DGAT1ALOX5APFEN1 | |
| SCHEMBL3926529 | 0.77 | IDO1 (0.36) | DGAT1IDO1TDO2ALOX5APFEN1 | |
| SCHEMBL2426784 | 0.76 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL3935350 | 0.76 | TACR1 (0.45) | — | |
| SCHEMBL3937390 | 0.75 | DGAT1 (0.33) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009009411-A1 | SUBSTITUTED HETEROCYCLIC ETHERS AND THEIR USE IN CNS DISORDERS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-15 | — | — | WO | disclosed |