SCHEMBL3923795

SCHEMBL3923795

C=C(C)C(=O)OCCC[SiH2]C(Oc1ccccc1)Oc1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.47
POLB P06746 1/20 0.47
APEX1 P27695 1/20 0.47
HTT P42858 1/20 0.47
TSHR P16473 3/20 0.41
MTNR1A P48039 2/20 0.37
MTNR1B P49286 2/20 0.37
ELANE P08246 1/20 0.37
THRB P10828 1/20 0.36
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
GAA P10253 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3923545 0.83 MTNR1A (0.40) TDP1POLBAPEX1HTTTSHR
SCHEMBL3101738 0.81 TDP1 (0.46) TDP1POLBAPEX1HTTTSHR
SCHEMBL1404303 0.77 TDP1 (0.68) TDP1POLBAPEX1HTTTSHR
SCHEMBL136875 0.77 TSHR (0.50) TDP1POLBAPEX1HTTTSHR
SCHEMBL4577427 0.77 TDP1 (0.73) TDP1POLBAPEX1HTTTSHR
SCHEMBL137795 0.76 TSHR (0.53) TDP1POLBAPEX1HTTTSHR
SCHEMBL28866107 0.76 TSHR (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL9093132 0.76 TSHR (0.49) TDP1POLBAPEX1HTTTSHR
SCHEMBL8038669 0.76 HTT (0.76) TDP1POLBAPEX1HTTTSHR
SCHEMBL8038704 0.76 HTT (0.76) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7619108-B2 Process for preparing unsaturated organosilicon compounds WACKER CHEMIE AG (DE) 2009-11-17 US disclosed
EP-1954701-B1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER CHEMIE AG (DE) 2009-03-18 EP disclosed
US-20080293958-A1 Process for Preparing Unsaturated Organosilicon Compounds WACKER CHEMIE AG (DE) 2008-11-27 US disclosed
US-6815554-B2 REACTING A HALOALKYLSILANE WITH A SALT OF AN UNSATURATED CARBOXYLIC ACID IN THE PRESENCE OF A PHASE TRANSFER CATALYST; BONDING AGENTS WACKER-CHEMIE GMBH (DE) 2004-11-09 US disclosed
US-20020151736-A1 PROCESS FOR PREPARING UNSATURATED ORGANOSILICON COMPOUNDS WACKER-CHEMIE GMBH (DE) 2002-10-17 US disclosed
EP-1249454-A1 Preparation of unsaturated organo-silicon compounds Wacker-Chemie GmbH (DE) 2002-10-16 EP disclosed