Sugi Predict

Sugi Predict / Compounds / SCHEMBL4577427

SCHEMBL4577427

SCHEMBL4577427

C=C(C)C(=O)OCCCCOc1ccccc1

nearest known ligand 0.73

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 2/20 0.73
▸ POLB P06746 1/20 0.73
▸ APEX1 P27695 1/20 0.73
▸ HTT P42858 1/20 0.73
▸ TSHR P16473 2/20 0.54
▸ KCNA3 P22001 1/20 0.53
▸ L3MBTL1 Q9Y468 2/20 0.53
▸ MTNR1A P48039 1/20 0.50
▸ MTNR1B P49286 1/20 0.50
▸ THRB P10828 1/20 0.49
▸ MMP2 P08253 2/20 0.48
▸ MMP9 P14780 2/20 0.48
▸ MMP12 P39900 2/20 0.48
▸ MMP1 P03956 1/20 0.48
▸ HDAC1 Q13547 2/20 0.47
▸ HDAC2 Q92769 2/20 0.47
▸ RECQL P46063 1/20 0.46
▸ PKM P14618 1/20 0.46
▸ GAA P10253 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8038704 0.98 HTT (0.76) TDP1POLBAPEX1HTTTSHR
SCHEMBL8038669 0.98 HTT (0.76) TDP1POLBAPEX1HTTTSHR
SCHEMBL1404303 0.97 TDP1 (0.68) TDP1POLBAPEX1HTTTSHR
Terephthalic Acid SCHEMBL7798065 0.93 HTT (0.86) TDP1POLBAPEX1HTTTSHR
SCHEMBL21371 0.92 TDP1 (0.61) TDP1POLBAPEX1HTTTSHR
SCHEMBL29316000 0.91 POLB (0.70) TDP1POLBAPEX1HTTTSHR
SCHEMBL28331865 0.90 TDP1 (0.60) TDP1POLBAPEX1HTTTSHR
SCHEMBL29316005 0.90 POLB (0.72) TDP1POLBAPEX1HTTTSHR
SCHEMBL29316003 0.90 POLB (0.72) TDP1POLBAPEX1HTTTSHR
Methacrylic Acid SCHEMBL17911799 0.89 TDP1 (0.58) TDP1POLBAPEX1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111467581-B Glaucoma drainage tube and preparation method thereof 广东赛珐生物科技有限公司 2022-04-12 — — CN claimed
CN-111467581-A Glaucoma drainage tube and preparation method thereof 广东赛珐生物科技有限公司 2020-07-31 — — CN claimed
US-6541572-B2 Copolymer containing oxirane graoups ALCON MANUFACTURING, LTD. 2003-04-01 — — US claimed
US-20020019492-A1 Method of making high refractive index ophthalmic device materials NOVARTIS AG (CH) 2002-02-14 — — US claimed
WO-2000079312-A1 HIGH REFRACTIVE INDEX COMPOSITIONS FOR OPHTHALMIC IMPLANTS BAUSCH & LOMB SURGICAL, INC. (US) 2000-12-28 — — WO claimed
WO-2025100122-A1 ELECTRODE PERIPHERAL EMBEDDING MATERIAL, PRE-BAKED FILM OF ELECTRODE PERIPHERAL EMBEDDING MATERIAL, METHOD FOR PRODUCING PRE-BAKED FILM OF ELECTRODE PERIPHERAL EMBEDDING MATERIAL, AND MICRO-LED DISPLAY ELEMENT 日産化学株式会社 2025-05-15 — — WO disclosed
WO-2025027810-A1 ELECTRODE PERIPHERAL EMBEDDED MATERIAL, ELECTRODE PERIPHERAL EMBEDDED MATERIAL PREBAKED FILM, METHOD FOR MANUFACTURING ELECTRODE PERIPHERAL EMBEDDED MATERIAL PREBAKED FILM, AND MICRO LED DISPLAY ELEMENT 日産化学株式会社 2025-02-06 — — WO disclosed
CN-115785735-B High-refractive-index ink for pure organic ink-jet printing and preparation method thereof 西安思摩威新材料有限公司 2024-04-26 — — CN disclosed
CN-117106374-A Glue composition and cured film formed by same 西安思摩威新材料有限公司 2023-11-24 — — CN disclosed
CN-115785735-A High-refractive-index ink for pure organic ink-jet printing and preparation method thereof 西安思摩威新材料有限公司 2023-03-14 — — CN disclosed
CN-115558429-A Glue composition and cured film formed by same 西安思摩威新材料有限公司 2023-01-03 — — CN disclosed
EP-2762506-B1 (METH)ACRYLOYL-TERMINATED POLYISOBUTYLENE POLYMER, METHOD FOR PRODUCING SAME, AND ACTIVE ENERGY RAY-CURABLE COMPOSITION KANEKA CORP (JP) 2022-09-07 — — EP disclosed
US-20080002146-A1 BIOCOMPATIBLE, SURFACE MODIFIED MATERIALS BAUSCH & LOMB INCORPORATED 2008-01-03 — — US disclosed
US-20070218104-A1 Rate controlled release of a pharmaceutical agent in a biodegradable device BAUSCH & LOMB INCORPORATION 2007-09-20 — — US disclosed
US-20070218103-A1 Rate controlled release of a pharmaceutical agent in a biodegradable device BAUSCH & LOMB INCORPORATED 2007-09-20 — — US disclosed
EP-1001720-B1 INTRACORNEAL DIFFRACTIVE LENS ALCON LAB INC (US) 2002-10-02 — — EP disclosed
WO-2002069849-A1 INTRACORNEAL LENS ALCON MANUFACTURING, LTD. (US) 2002-09-12 — — WO disclosed
US-20010018612-A1 Intracorneal lens ALCON MANUFACTURING, LTD. 2001-08-30 — — US disclosed
EP-1001720-A1 INTRACORNEAL DIFFRACTIVE LENS ALCON LABORATORIES, INC. (US) 2000-05-24 — — EP disclosed
WO-1999007309-A1 INTRACORNEAL DIFFRACTIVE LENS ALCON LABORATORIES, INC. (US) 1999-02-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070218104-A1 Rate controlled release of a pharmaceutical agent in a biodegradable device IDUA, ACMSD, MLEC TDP1 1305/4885POLB 1540/4885APEX1 3679/4885
US-20070218103-A1 Rate controlled release of a pharmaceutical agent in a biodegradable device IDUA, APEH, PAM TDP1 1120/4885POLB 1396/4885APEX1 3350/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.