SCHEMBL3923892

SCHEMBL3923892

O=C(O)[C@H](Cc1ccc(O)cc1)Nc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARG P37231 1/20 0.56
MME P08473 4/20 0.56
FOLH1 Q04609 1/20 0.52
NAALAD2 Q9Y3Q0 1/20 0.52
ACE P12821 8/20 0.52
SLC7A5 Q01650 1/20 0.50
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
CPA1 P15085 1/20 0.48
ACE2 Q9BYF1 1/20 0.48
ITGB1 P05556 1/20 0.47
ITGA4 P13612 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18351661 1.00 PPARG (0.56) PPARGMMEFOLH1NAALAD2ACE
SCHEMBL3923887 1.00 PPARG (0.56) PPARGMMEFOLH1NAALAD2ACE
Hydroquinone SCHEMBL28778306 0.97 PPARG (0.56) PPARGMMEFOLH1NAALAD2ACE
SCHEMBL28789648 0.93 PPARG (0.60) PPARGMMEFOLH1NAALAD2ACE
SCHEMBL28789647 0.93 PPARG (0.60) PPARGMMEFOLH1NAALAD2ACE
SCHEMBL1533645 0.90 PPARG (0.58) PPARGMMEFOLH1NAALAD2
SCHEMBL1533647 0.90 PPARG (0.58) PPARGMMEFOLH1NAALAD2
SCHEMBL6250861 0.90 PPARG (0.58) PPARGMMEFOLH1NAALAD2
Phenylalanine SCHEMBL8974614 0.87 SLC7A5 (0.65) PPARGMMEACESLC7A5
SCHEMBL11276580 0.86 MME (0.53) PPARGMMEFOLH1NAALAD2ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113293151-A Short-chain dehydrogenase mutants and uses thereof 沈阳药科大学 2021-08-24 CN claimed
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS INC (US) 2026-04-30 US disclosed
US-12552836-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases PROTAGONIST THERAPEUTICS, INC. (US) 2026-02-17 US disclosed
US-12216122-B2 Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (IDO1) REGENERON PHARMACEUTICALS, INC. (US) 2025-02-04 US disclosed
US-20240383954-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES JANSSEN BIOTECH INC (US) 2024-11-21 US disclosed
CN-115785124-A KRAS G12D inhibitors and uses thereof 润佳(苏州)医药科技有限公司 2023-03-14 CN disclosed
CN-115053184-A Composition for forming EUV resist underlayer film 日产化学株式会社 2022-09-13 CN disclosed
CN-113293151-B Short-chain dehydrogenase mutants and uses thereof 沈阳药科大学 2022-06-07 CN disclosed
CN-113293152-B Short-chain dehydrogenase mutant and use thereof 沈阳药科大学 2022-05-20 CN disclosed
US-20220041658-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES PROTAGONIST THERAPEUTICS, INC. 2022-02-10 US disclosed
CN-113293151-A Short-chain dehydrogenase mutants and uses thereof 沈阳药科大学 2021-08-24 CN disclosed
CN-113293152-A Short-chain dehydrogenase mutants and uses thereof 沈阳药科大学 2021-08-24 CN disclosed
CN-108570460-B Short-chain dehydrogenase mutants and uses thereof 沈阳药科大学 2021-07-30 CN disclosed
US-9534016-B2 Netrin loop peptide mimetics and uses thereof BUCK INSTITUTE FOR RESEARCH ON AGING (US) 2017-01-03 US disclosed
WO-2009009035-A1 SOMATOSTATIN ANALOG AND USES THEREOF IPSEN PHARMA S.A.S. (FR) 2009-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12216122-B2 Compositions and methods relating to detection, inhibition, and imaging of indoleamine 2,3-dioxygenase 1 (IDO1) IDO1, IDO2, KYNU PPARG 4816/4885MME 287/4885FOLH1 101/4885
US-12552836-B2 Peptide inhibitors of interleukin-23 receptor and their use to treat inflammatory diseases IL23R, IL17A, IL36G PPARG 2233/4885MME 47/4885FOLH1 1213/4885
US-20220041658-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, VIP PPARG 1731/4885MME 299/4885FOLH1 640/4885
US-20240383954-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, VIP PPARG 1731/4885MME 299/4885FOLH1 640/4885
US-20260116921-A1 PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR AND THEIR USE TO TREAT INFLAMMATORY DISEASES IL23R, IL1RN, IL36G PPARG 2135/4885MME 15/4885FOLH1 3178/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.