Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | CHUK | O15111 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932276 | 0.79 | MEN1 (0.53) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL3927501 | 0.78 | SOAT1 (0.37) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL3929052 | 0.78 | PTPN11 (0.36) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL5929953 | 0.76 | MEN1 (0.50) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL4461566 | 0.76 | MEN1 (0.50) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL3469016 | 0.76 | MEN1 (0.50) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL10430488 | 0.76 | MEN1 (0.50) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL3935979 | 0.75 | LTA4H (0.47) | LMNAMAPTALDH1A1HPGDHTT | |
| SCHEMBL11342206 | 0.75 | CYP1A2 (0.49) | MEN1KMT2ANR1I2LMNACHRM2 | |
| SCHEMBL22090628 | 0.73 | CNR2 (0.43) | MEN1KMT2ANR1I2LMNACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1313785-B1 | COMPOSITION COMPRISING IPTYCENE POLYMERS WITH HIGH INTERNAL VOLUME | MASSACHUSETTS INST TECHNOLOGY (US) | 2009-04-01 | — | — | EP | disclosed |
| US-7494698-B2 | Polymers with high internal free volume | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2009-02-24 | — | — | US | disclosed |
| US-20080188634-A1 | Polymers with high internal free volume | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2008-08-07 | — | — | US | disclosed |
| US-20040170775-A1 | Polymers with high internal free volume | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-09-02 | — | — | US | disclosed |
| US-6783814-B2 | GRAFT POLYMER OF POROUS POLYMER AND INTERPENETRATING POLYMER NETWORK | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2004-08-31 | — | — | US | disclosed |
| US-20020150697-A1 | Polymers with high internal free volume | NAVY, SECRETARY OF THE, UNITED STATES OF AMERICA | 2002-10-17 | — | — | US | disclosed |