Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.57 |
| ▸ | ADH1C | P00326 | 2/20 | 0.57 |
| ▸ | ADH1A | P07327 | 2/20 | 0.57 |
| ▸ | ADH7 | P40394 | 2/20 | 0.57 |
| ▸ | ADH4 | P08319 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.35 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | DRD3 | P35462 | 2/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24510986 | 1.00 | ADH1B (0.57) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL3927921 | 0.89 | ADH1B (0.50) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL3928885 | 0.81 | ADH1B (0.52) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL4874323 | 0.80 | SMN1; SMN2 (0.37) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL3318099 | 0.80 | ADH1B (0.50) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL3316370 | 0.80 | ADH1B (0.50) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL3317295 | 0.80 | ADH1B (0.50) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL1911418 | 0.79 | ADH1B (0.57) | ADH1BADH1CADH1AADH7ADH4 | |
| SCHEMBL1608989 | 0.77 | — | — | |
| SCHEMBL9962292 | 0.77 | SAT1 (0.38) | SMN1; SMN2KCNH2CHRM2ADRA2ACHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023235384-A1 | COMPOUNDS FOR ENHANCING READ THROUGH OF GENES CONTAINING PREMATURE TERMINATION CODONS AND METHODS FOR MAKING AND USING THE SAME | SANOFI US SERVICES INC. (US) | 2023-12-07 | — | — | WO | disclosed |
| EP-3319960-B1 | PYRIMIDINE DERIVATIVES AS BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2020-11-18 | — | — | EP | disclosed |
| WO-2009007390-A2 | 2-PYRAZ INYLBENZ IMIDAZOLE DERIVATIVES AS RECEPTOR TYROSINE KINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | WO | disclosed |