Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 2/20 | 0.50 |
| ▸ | ADH1C | P00326 | 2/20 | 0.50 |
| ▸ | ADH1A | P07327 | 2/20 | 0.50 |
| ▸ | ADH4 | P08319 | 1/20 | 0.50 |
| ▸ | ADH7 | P40394 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.37 |
| ▸ | CCR2 | P41597 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.33 |
| ▸ | GHSR | Q92847 | 8/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3317295 | 1.00 | ADH1B (0.50) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL3316370 | 1.00 | ADH1B (0.50) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL20807878 | 0.90 | ADH1B (0.44) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL12095082 | 0.90 | ADH1B (0.44) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL24535944 | 0.80 | KCNH2 (0.38) | KCNH2CCR2CYP2D6GHSRKAT2B | |
| SCHEMBL24510986 | 0.80 | ADH1B (0.57) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL3924693 | 0.80 | ADH1B (0.57) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL17827393 | 0.80 | KCNH2 (0.37) | KCNH2CCR2CYP2D6GHSRKAT2B | |
| SCHEMBL3317300 | 0.80 | KCNH2 (0.37) | KCNH2CCR2CYP2D6GHSRKAT2B | |
| SCHEMBL3316366 | 0.80 | KCNH2 (0.37) | KCNH2CCR2CYP2D6GHSRKAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | 4SC AG (DE) | 2010-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100104659-A1 | BENZOPYRANOPYRAZOLES | BAX, BCL2, BAD | ADH1B 1255/4885ADH1C 2915/4885ADH1A 1695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.