⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3928014 | 0.90 | — | — | |
| SCHEMBL5985780 | 0.88 | RAB9A (0.31) | — | |
| SCHEMBL5986289 | 0.88 | RAB9A (0.31) | — | |
| SCHEMBL5984884 | 0.88 | RAB9A (0.31) | — | |
| SCHEMBL5983964 | 0.88 | RAB9A (0.31) | — | |
| SCHEMBL5985239 | 0.88 | RAB9A (0.31) | — | |
| SCHEMBL5855746 | 0.88 | RAB9A (0.31) | — | |
| SCHEMBL5984438 | 0.88 | RAB9A (0.31) | — | |
| SCHEMBL5986074 | 0.88 | RAB9A (0.31) | — | |
| SCHEMBL5985221 | 0.88 | RAB9A (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009005839-A2 | COMPOUNDS AND METHODS OF USE | THE GOVERNMENT OF THE U.S.A. AS REPRESENTED BY THE SECRETARY OF THE DEPT. OF HEALTH & HUMAN SERVICE (US) | 2009-01-08 | — | — | WO | claimed |
| WO-2023234427-A1 | ANTIBODY-MULTIDRUG CONJUGATE PRECURSOR AND SYNTHETIC INTERMEDIATE THEREOF | ＵＢＥ株式会社 | 2023-12-07 | — | — | WO | disclosed |
| WO-2023234426-A1 | ANTIBODY-MULTIDRUG CONJUGATE | ＵＢＥ株式会社 | 2023-12-07 | — | — | WO | disclosed |
| WO-2023163234-A1 | ANTIBODY-DRUG CONJUGATE PRECURSOR AND INTERMEDIATE FOR SYNTHESIS THEREOF | ＵＢＥ株式会社 | 2023-08-31 | — | — | WO | disclosed |
| WO-2023163227-A1 | ANTIBODY-DRUG CONJUGATE | ＵＢＥ株式会社 | 2023-08-31 | — | — | WO | disclosed |
| WO-2023140369-A1 | PHOSPHORIC ACID DERIVATIVES | Prism BioLab Co., Ltd. (JP) | 2023-07-27 | — | — | WO | disclosed |
| US-9707540-B2 | Metal-organic materials and method for preparation | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2017-07-18 | — | — | US | disclosed |
| US-9611218-B2 | Metal-organic materials and method for preparation | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2017-04-04 | — | — | US | disclosed |
| US-20160271582-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-09-22 | — | — | US | disclosed |
| US-20160152568-A1 | METAL-ORGANIC MATERIALS AND METHOD FOR PREPARATION | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2016-06-02 | — | — | US | disclosed |
| EP-0570594-A1 | HYDROXAMIC ACID DERIVATIVE BASED ON AROMATIC SULFONAMIDE | SHIONOGI & CO., LTD. (JP) | 1993-11-24 | — | — | EP | disclosed |
| EP-0570245-A2 | Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1993-11-18 | — | — | EP | disclosed |
| EP-0314435-B1 | OCTAHYDRONAPHTHALENE OXIME DERIVATIVES FOR CHOLESTEROL SYNTHESIS INHIBITION, PROCESSES FOR THEIR PREPARATION AND COMPOSITIONS CONTAINING THEM | Sankyo Company Limited (JP) | 1993-09-29 | — | — | EP | disclosed |
| US-5120738-A | Cardiovascular disorders | FUJIREBIO INC. (JP) | 1992-06-09 | — | — | US | disclosed |
| US-5039674-A | Calcium antagonistics | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1991-08-13 | — | — | US | disclosed |
| EP-0421441-A2 | Pantothenic acid derivatives | FUJIREBIO INC. (JP) | 1991-04-10 | — | — | EP | disclosed |
| US-4997848-A | Enzyme inhibitors | SANKYO COMPANY, LIMITED (JP) | 1991-03-05 | — | — | US | disclosed |
| EP-0314435-A2 | Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition, processes for their preparation and compositions containing them | Sankyo Company Limited (JP) | 1989-05-03 | — | — | EP | disclosed |
| US-4782160-A | CALCIUM RECEPTOR ANTAGONISTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1988-11-01 | — | — | US | disclosed |
| EP-0276552-A1 | 1,4-dihydropyridine derivatives and their production | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1988-08-03 | — | — | EP | disclosed |