Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | MGAM | O43451 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SI | P14410 | 1/20 | 0.37 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12505866 | 0.92 | RNPEP (0.38) | ALDH1A1TP53SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL234333 | 0.91 | ALDH1A1 (0.37) | ALDH1A1TP53SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL10623678 | 0.82 | ALDH1A1 (0.40) | ALDH1A1TP53SMN1; SMN2LMNAHSD17B10 | |
| SCHEMBL1419923 | 0.82 | SMN1; SMN2 (0.36) | ALDH1A1TP53SMN1; SMN2LMNAMAPT | |
| SCHEMBL2460611 | 0.77 | ALDH1A1 (0.56) | ALDH1A1LMNAHSD17B10MAPTKMT2A | |
| SCHEMBL9271930 | 0.76 | CYP3A4 (0.49) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL265127 | 0.76 | CYP3A4 (0.49) | ALDH1A1LMNAHSD17B10ALOX15MGAM | |
| SCHEMBL335607 | 0.76 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10KMT2AALOX15 | |
| SCHEMBL233700 | 0.76 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2LMNAHSD17B10ALOX15 | |
| SCHEMBL335361 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TP53SMN1; SMN2LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009004643-A2 | AN IMPROVED PROCESS FOR PREPARATION OF (S)-PREGABALIN AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2009-01-08 | — | — | WO | claimed |
| WO-2009004643-A2 | AN IMPROVED PROCESS FOR PREPARATION OF (S)-PREGABALIN AND INTERMEDIATES THEREOF | CADILA HEALTHCARE LIMITED (IN) | 2009-01-08 | — | — | WO | disclosed |