Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.38 |
| ▸ | RELA | Q04206 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12662934 | 0.81 | KDM4E (0.49) | KDM4EALDH1A1L3MBTL1SMN1; SMN2NFKB1 | |
| SCHEMBL13909144 | 0.79 | KDM4E (0.38) | KDM4EALDH1A1L3MBTL1SMN1; SMN2NFKB1 | |
| SCHEMBL4889842 | 0.78 | ALDH1A1 (0.43) | KDM4EALDH1A1L3MBTL1RXRARXRB | |
| SCHEMBL13268136 | 0.78 | KDM4E (0.51) | KDM4EALDH1A1L3MBTL1SMN1; SMN2NPC1 | |
| SCHEMBL17477885 | 0.76 | KDM4E (0.50) | KDM4EALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL958610 | 0.75 | SMN1; SMN2 (0.50) | KDM4EALDH1A1L3MBTL1SMN1; SMN2NFKB1 | |
| SCHEMBL27594360 | 0.73 | KDM4E (0.47) | KDM4EALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL4670524 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1L3MBTL1SMN1; SMN2MAPT | |
| SCHEMBL18291548 | 0.70 | SMN1; SMN2 (0.49) | KDM4EALDH1A1L3MBTL1SMN1; SMN2NFKB1 | |
| SCHEMBL14022008 | 0.69 | KDM4E (0.58) | KDM4EALDH1A1L3MBTL1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2040703-A2 | DERIVATIVES OF 2-BENZOYL-IMIDAZOPYRIDINES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | Sanofi-Aventis (FR) | 2009-04-01 | — | — | EP | disclosed |
| WO-2008003854-A2 | DERIVATIVES OF 2-BENZOYL-IMIDAZOPYRIDINES, PREPARATION METHOD THEREOF AND USE OF SAME IN THERAPEUTICS | SANOFI-AVENTIS (FR) | 2008-01-10 | — | — | WO | disclosed |