Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 4/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GLS | O94925 | 2/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.38 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3925572 | 1.00 | ALDH1A1 (0.51) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL3915731 | 0.87 | ALDH1A1 (0.50) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL3915734 | 0.87 | ALDH1A1 (0.50) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL4112764 | 0.84 | ALDH1A1 (0.46) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL7881141 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL2801381 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL30032505 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL2801378 | 0.84 | ALDH1A1 (0.48) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL7545798 | 0.83 | ALDH1A1 (0.47) | ALDH1A1GAAHTTNPC1LMNA | |
| SCHEMBL16481096 | 0.81 | ALDH1A1 (0.55) | ALDH1A1GAAHTTNPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7517876-B2 | Anti-infective agents | ABBOTT LABORATORIES (US) | 2009-04-14 | — | — | US | disclosed |
| US-20060287300-A1 | Anti-infective agents | ABBVIE INC. | 2006-12-21 | — | — | US | disclosed |
| WO-2006093801-A1 | THIADIAZINE DERIVATIVES USEFUL AS ANTI-INFECTIVE AGENTS | ABBOTT LABORATORIES (US) | 2006-09-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287300-A1 | Anti-infective agents | RPL5, POLI, RPL35 | ALDH1A1 2009/4885GAA 122/4885HTT 4064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.