Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 7/20 | 0.51 |
| ▸ | NOS1 | P29475 | 3/20 | 0.50 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 3/20 | 0.44 |
| ▸ | NOS3 | P29474 | 1/20 | 0.44 |
| ▸ | NOS2 | P35228 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3998820 | 0.86 | NOS1 (0.48) | ALOX5NOS1AOC3TAAR1GRIN2D | |
| SCHEMBL1744969 | 0.82 | NOS1 (0.52) | NOS1AOC3TAAR1GRIN2DGRIN3B | |
| SCHEMBL10592047 | 0.80 | AOC3 (0.55) | NOS1AOC3TAAR1GRIN2DGRIN3B | |
| SCHEMBL6378572 | 0.79 | GRIN2D (0.56) | ALOX5NOS1AOC3GRIN2DGRIN3B | |
| SCHEMBL3916717 | 0.78 | NOS1 (0.48) | NOS1AOC3TAAR1GRIN2DGRIN3B | |
| SCHEMBL17887716 | 0.77 | GRIN2D (0.64) | NOS1AOC3TAAR1GRIN2DGRIN3B | |
| SCHEMBL9373618 | 0.77 | ALOX5 (0.57) | ALOX5AOC3 | |
| SCHEMBL1520687 | 0.75 | ALOX5 (0.65) | ALOX5AOC3TAAR1CYP1A2CYP3A4 | |
| SCHEMBL11643863 | 0.74 | NOS1 (0.44) | NOS1AOC3TAAR1GRIN2DGRIN3B | |
| SCHEMBL27914440 | 0.74 | ALOX5 (0.63) | ALOX5AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3911372-A1 | COMPOUND TARGETING NOREPINEPHRINE TRANSPORTER | Guangzhou Miphere Medical Technology Co., Ltd. (CN) | 2021-11-24 | — | — | EP | disclosed |
| WO-2020148154-A1 | COMPOUND TARGETING NOREPINEPHRINE TRANSPORTER | JULIUS-MAXIMILIANS-UNIVERSITAET WUERZBURG (DE) | 2020-07-23 | — | — | WO | disclosed |
| US-7534418-B2 | Imaging agents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2009-05-19 | — | — | US | disclosed |
| US-20060127309-A1 | Imaging agents | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060127309-A1 | Imaging agents | MPI, NPC1, NPC1L1 | ALOX5 3762/4885NOS1 3046/4885AOC3 3108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.