Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | THRB | P10828 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2775308 | 0.74 | TSHR (0.45) | TSHRHPGDALDH1A1THRBTP53 | |
| SCHEMBL3284080 | 0.74 | TSHR (0.43) | TSHRHPGDALDH1A1THRBTP53 | |
| SCHEMBL8563118 | 0.74 | — | — | |
| SCHEMBL27932407 | 0.72 | — | — | |
| SCHEMBL3924387 | 0.72 | ALDH1A1 (0.38) | TSHRALDH1A1THRB | |
| Hydrochloric Acid SCHEMBL27955705 | 0.71 | TSHR (0.41) | TSHRHPGDALDH1A1THRBTP53 | |
| Bromide SCHEMBL30406489 | 0.71 | TSHR (0.41) | TSHRHPGDALDH1A1THRBTP53 | |
| SCHEMBL18839966 | 0.69 | TSHR (0.39) | TSHRHPGDALDH1A1THRBTP53 | |
| SCHEMBL6964832 | 0.69 | — | — | |
| SCHEMBL17965912 | 0.69 | TSHR (0.39) | TSHRHPGDALDH1A1THRBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3645540-A1 | SILOLE AND GERMOLE FUSED RING PHOTOCHROMIC COMPOUNDS | Transitions Optical, Ltd. (IE) | 2020-05-06 | — | — | EP | claimed |
| WO-2019001724-A1 | SILOLE AND GERMOLE FUSED RING PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL, LTD. (IE) | 2019-01-03 | — | — | WO | claimed |
| JP-9031183-A | — | — | None | — | — | JP | disclosed |
| CN-115197448-A | Spherical powder comprising crosslinked material having polyrotaxane, and method for producing same | 株式会社ASM | 2022-10-18 | — | — | CN | disclosed |
| CN-109843986-B | Spherical powder comprising crosslinked material having polyrotaxane, and method for producing same | 株式会社ASM | 2022-08-16 | — | — | CN | disclosed |
| US-11053357-B2 | Spherical powder containing crosslinked body formed having polyrotaxane, and method for producing same | ASM INC. (JP) | 2021-07-06 | — | — | US | disclosed |
| US-20190345294-A1 | SPHERICAL POWDER CONTAINING CROSSLINKED BODY FORMED HAVING POLYROTAXANE, AND METHOD FOR PRODUCING SAME | ADVANCED SOFTMATERIALS INC. (JP) | 2019-11-14 | — | — | US | disclosed |
| EP-3527610-A1 | SPHERICAL POWDER CONTAINING CROSSLINKED BODY FORMED HAVING POLYROTAXANE, AND METHOD FOR PRODUCING SAME | Advanced Softmaterials Inc. (JP) | 2019-08-21 | — | — | EP | disclosed |
| EP-3071551-A1 | FUSED RING INDENO COMPOUNDS FOR PREPARATION OF PHOTOCHROMIC COMPOUNDS | Transitions Optical, Inc. (US) | 2016-09-28 | — | — | EP | disclosed |
| WO-2015077141-A1 | FUSED RING INDENO COMPOUNDS FOR PREPARATION OF PHOTOCHROMIC COMPOUNDS | TRANSITIONS OPTICAL, INC. (US) | 2015-05-28 | — | — | WO | disclosed |
| JP-2009155322-A | AROMATIC RING-CONTAINING MONOMER COMPOSITION AND POLYMER BASED THEREON | OSAKA ORGANIC CHEM IND LTD | 2009-07-16 | — | — | JP | disclosed |
| JP-H0931183-A | PHOTO-SETTING BIODEGRADABLE RESIN AND PRODUCTION THEREOF | TOPPAN PRINTING CO LTD | 1997-02-04 | — | — | JP | disclosed |