SCHEMBL39287

SCHEMBL39287

C=CNc1ccc(C(=O)c2ccccc2)cc1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK13 O15264 2/20 0.60
MAPK12 P53778 2/20 0.60
MAPK11 Q15759 2/20 0.60
MAPK14 Q16539 2/20 0.60
RAB9A P51151 6/20 0.56
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
NPC1 O15118 3/20 0.56
ALDH1A1 P00352 8/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
HPGD P15428 5/20 0.53
LMNA P02545 3/20 0.53
MAPT P10636 2/20 0.53
SRD5A2 P31213 1/20 0.52
FFAR1 O14842 1/20 0.51
SMN1; SMN2 Q16637 3/20 0.50
NPSR1 Q6W5P4 2/20 0.50
HTT P42858 1/20 0.50
ATM Q13315 1/20 0.47
TDP1 Q9NUW8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12882616 0.82 MAPK13 (0.62) MAPK13MAPK12MAPK11MAPK14RAB9A
SCHEMBL39036 0.78 TGM2 (0.72) MAPK13MAPK12MAPK11MAPK14RAB9A
SCHEMBL10601664 0.78 MAPT (0.54) RAB9AMEN1KMT2ANPC1ALDH1A1
SCHEMBL29196087 0.77 MAPK13 (0.95) MAPK13MAPK12MAPK11MAPK14RAB9A
SCHEMBL304279 0.76
SCHEMBL9066312 0.76 ALDH1A1 (0.93) MAPK13MAPK12MAPK11MAPK14RAB9A
SCHEMBL314267 0.76 ALDH1A1 (0.93) MAPK13MAPK12MAPK11MAPK14RAB9A
SCHEMBL5154269 0.75 MAPK13 (1.00) MAPK13MAPK12MAPK11MAPK14RAB9A
SCHEMBL29042747 0.75 MAPK13 (0.76) MAPK13MAPK12MAPK11MAPK14RAB9A
SCHEMBL12522066 0.75 MAPK13 (0.69) MAPK13MAPK12MAPK11MAPK14RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10011688-B2 Hydrophilic gels derived from grafted photoinitiators COLOPLAST A/S (DK) 2018-07-03 US disclosed
US-10011688-B2 Hydrophilic gels derived from grafted photoinitiators COLOPLAST A/S (DK) 2018-07-03 US disclosed
US-9670373-B2 Polymers comprising photoinitiator moieties and dye moieties LAMBSON LIMITED (GB) 2017-06-06 US disclosed
US-9464143-B2 Grafted photoinitiators COLOPLAST A/S (DK) 2016-10-11 US disclosed
US-9464143-B2 Grafted photoinitiators COLOPLAST A/S (DK) 2016-10-11 US disclosed
US-20160168336-A1 HYDROPHILIC GELS DERIVED FROM GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2016-06-16 US disclosed
US-20160168336-A1 HYDROPHILIC GELS DERIVED FROM GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2016-06-16 US disclosed
US-9303129-B2 Hydrophilic gels derived from grafted photoinitiators COLOPLAST A/S (DK) 2016-04-05 US disclosed
US-9303129-B2 Hydrophilic gels derived from grafted photoinitiators COLOPLAST A/S (DK) 2016-04-05 US disclosed
EP-2744834-B1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES LAMBSON LTD (GB) 2014-12-24 EP disclosed
EP-2585496-A2 HYDROPHILIC GELS DERIVED FROM GRAFTED PHOTOINITIATORS Coloplast A/S (DK) 2013-05-01 EP disclosed
US-20130096220-A1 GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-18 US disclosed
US-20130096220-A1 GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-18 US disclosed
US-20130096221-A1 HYDROPHILIC GELS DERIVED FROM GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-18 US disclosed
US-20130096221-A1 HYDROPHILIC GELS DERIVED FROM GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2013-04-18 US disclosed
WO-2013026451-A1 POLYMERS COMPRISING PHOTOINITIATOR MOIETIES AND DYE MOIETIES COLOPLAST A/S (DK) 2013-02-28 WO disclosed
WO-2011160636-A2 GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed
WO-2011160636-A2 GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed
WO-2011160640-A2 HYDROPHILIC GELS DERIVED FROM GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed
WO-2011160640-A2 HYDROPHILIC GELS DERIVED FROM GRAFTED PHOTOINITIATORS COLOPLAST A/S (DK) 2011-12-29 WO disclosed