SCHEMBL3929045

SCHEMBL3929045

CCOC(c1ccccn1)C([SiH3])(OCC)OCC

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA5 P22460 3/20 0.41
KCNH2 Q12809 2/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
TSHR P16473 1/20 0.39
CYP2D6 P10635 2/20 0.39
KCNE1 P15382 1/20 0.39
ALDH1A1 P00352 1/20 0.37
CYP1A2 P05177 1/20 0.37
SLC6A2 P23975 3/20 0.36
SLC6A4 P31645 3/20 0.36
SLC6A3 Q01959 2/20 0.36
CHRM2 P08172 2/20 0.35
SCN1A P35498 1/20 0.35
SCN2A Q99250 1/20 0.35
SCN3A Q9NY46 1/20 0.35
LMNA P02545 3/20 0.35
CYP2C19 P33261 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27827264 0.86 MEN1 (0.40) KCNA5KCNH2MEN1KMT2AGAA
SCHEMBL21742017 0.82 KCNH2 (0.44) KCNA5KCNH2MEN1KMT2AGAA
SCHEMBL27970656 0.81 KCNA5 (0.42) KCNA5KCNH2MEN1KMT2AGAA
SCHEMBL21742064 0.81 KCNA5 (0.42) KCNA5KCNH2MEN1KMT2AGAA
SCHEMBL4245934 0.77 L3MBTL1 (0.36) KCNH2SMN1; SMN2TSHRCYP2D6CYP1A2
SCHEMBL16343820 0.74 FFAR1 (0.33) SLC6A2SLC6A4SLC6A3
SCHEMBL28012567 0.74 KCNA5 (0.49) KCNA5KCNH2MEN1KMT2AGAA
SCHEMBL15704684 0.74 KCNA5 (0.49) KCNA5KCNH2MEN1KMT2AGAA
SCHEMBL15280655 0.73 KCNA5 (0.47) KCNA5KCNH2MEN1KMT2AGAA
SCHEMBL4028597 0.72 SLC6A3 (0.39) KCNA5KCNH2MEN1KMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7528199-B2 Conjugated-diolefin (co)polymer rubber and process for producing the same JSR CORPORATION (JP) 2009-05-05 US claimed
US-7528199-B2 Conjugated-diolefin (co)polymer rubber and process for producing the same JSR CORPORATION (JP) 2009-05-05 US disclosed
US-20070088132-A1 Conjugated-diolefin (co)polymer rubber and process for producing the same JSR CORPORATION (JP) 2007-04-19 US disclosed