SCHEMBL392930

SCHEMBL392930

O=S(=O)(O)c1c2ccccc2cc2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.61
ALDH1A1 P00352 4/20 0.48
HSD17B10 Q99714 4/20 0.48
CYP1A2 P05177 3/20 0.48
CYP2C19 P33261 2/20 0.48
MEN1 O00255 2/20 0.48
KMT2A Q03164 2/20 0.48
HPGD P15428 2/20 0.48
KDM4E B2RXH2 1/20 0.48
GLA P06280 1/20 0.48
MPL P40238 3/20 0.42
HIF1A Q16665 2/20 0.42
CYP2C9 P11712 1/20 0.42
ALOX15 P16050 1/20 0.42
ATIC P31939 1/20 0.42
CTRC Q99895 1/20 0.42
CYP3A4 P08684 1/20 0.42
TRPM4 Q8TD43 1/20 0.41
CYP1B1 Q16678 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8157500 0.98 CYP2D6 (0.59) CYP2D6ALDH1A1HSD17B10CYP1A2CYP2C19
Hydrochloric Acid SCHEMBL27596429 0.98 CYP2D6 (0.59) CYP2D6ALDH1A1HSD17B10CYP1A2CYP2C19
SCHEMBL8157494 0.98 CYP2D6 (0.59) CYP2D6ALDH1A1HSD17B10CYP1A2CYP2C19
SCHEMBL31398447 0.85 CYP2D6 (0.56) CYP2D6ALDH1A1HSD17B10CYP1A2CYP2C19
SCHEMBL219389 0.85 CYP2D6 (0.56) CYP2D6ALDH1A1HSD17B10CYP1A2CYP2C19
SCHEMBL15851415 0.85 CYP2D6 (0.51) CYP2D6ALDH1A1HSD17B10CYP1A2CYP2C19
SCHEMBL10930603 0.84 CYP2D6 (0.48) CYP2D6ALDH1A1HSD17B10CYP1A2CYP2C19
SCHEMBL14813073 0.84 CYP2D6 (0.54) CYP2D6ALDH1A1HSD17B10CYP1A2CYP2C19
SCHEMBL1247911 0.84 CYP2D6 (0.54) CYP2D6ALDH1A1HSD17B10CYP1A2CYP2C19
SCHEMBL564215 0.84 CYP2D6 (0.58) CYP2D6ALDH1A1HSD17B10CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 128 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111138416-A Preparation method of L-sunitinib malate E-type isomer 南京华威医药科技集团有限公司 2020-05-12 CN claimed
EP-1844010-B1 ISOMERISATION OF PHARMACEUTICAL INTERMEDIATES LEO PHARMA AS (DK) 2013-02-13 EP claimed
CN-101400649-B Isomerization of pharmaceutical intermediates LEO PHARMA AS 2012-07-04 CN claimed
US-8100020-B2 Compliant and wireless health monitoring sensors for composite structures Lumimove, Inc., a Missouri Corporation (US) 2012-01-24 US claimed
US-20100095781-A1 COMPLIANT AND WIRELESS HEALTH MONITORING SENSORS FOR COMPOSITE STRUCTURES LUMIMOVE, INC., D/B/A CROSSLINK (US) 2010-04-22 US claimed
CN-101400649-A Isomerization of pharmaceutical intermediates LEO PHARMA AS (DK) 2009-04-01 CN claimed
EP-1844010-A1 ISOMERISATION OF PHARMACEUTICAL INTERMEDIATES LEO PHARMA A/S (DK) 2007-10-17 EP claimed
US-20070215455-A1 Isomerisation of pharmaceutical intermediates LEO PHARMA A/S (DK) 2007-09-20 US claimed
WO-2007082533-A1 ISOMERISATION OF PHARMACEUTICAL INTERMEDIATES LEO PHARMA A/S (DK) 2007-07-26 WO claimed
US-4548907-A Fluorescent fluid determination method and apparatus ALLIED CORPORATION (US) 1985-10-22 US claimed
EP-0137157-A2 Fluid analysis technology using fluorescence type sensors Fisher Scientific Company (US) 1985-04-17 EP claimed
US-20240231230-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST UNDERLAYER FILM NISSAN CHEMICAL CORPORATION (JP) 2024-07-11 US disclosed
WO-2024116910-A1 COMPOSITION AND METHOD FOR ENHANCING SILICON NITRIDE POLISHING RATE SELECTIVITY 株式会社フジミインコーポレーテッド 2024-06-06 WO disclosed
WO-2023189799-A1 SELF CROSS-LINKABLE POLYMER AND RESIST UNDERLAYER FILM-FORMING COMPOSITION 日産化学株式会社 2023-10-05 WO disclosed
WO-2023189803-A1 RESIST UNDERLAYER FILM FORMING COMPOSITION 日産化学株式会社 2023-10-05 WO disclosed
WO-1990010297-A1 THERMALLY STABLE FORMS OF ELECTRICALLY CONDUCTIVE POLYANILINE ALLIED-SIGNAL INC. (US) 1990-09-07 WO disclosed
EP-0062611-B1 PHOTOPOLYMERISATION PROCESS CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed
EP-0137157-A2 Fluid analysis technology using fluorescence type sensors Fisher Scientific Company (US) 1985-04-17 EP disclosed
US-4413052-A Photopolymerization process employing compounds containing acryloyl group and anthryl group CIBA-GEIGY CORPORATION (US) 1983-11-01 US disclosed
EP-0062611-A2 Photopolymerisation process CIBA-GEIGY AG (CH) 1982-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070215455-A1 Isomerisation of pharmaceutical intermediates CYP24A1, CYP2R1, VDR CYP2D6 48/4885ALDH1A1 532/4885HSD17B10 242/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.