Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | GABRE | P78334 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19815499 | 1.00 | ALDH1A1 (0.63) | ALDH1A1SMN1; SMN2TSHRGABRPGABRD | |
| Hydrochloric Acid SCHEMBL16823920 | 0.98 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2TSHRGABRPGABRD | |
| SCHEMBL10859973 | 0.85 | ALDH1A1 (0.71) | ALDH1A1SMN1; SMN2HTR2AHRH1HTR2C | |
| SCHEMBL5912608 | 0.84 | KMT2A (0.46) | ALDH1A1SMN1; SMN2LMNAL3MBTL3L3MBTL1 | |
| SCHEMBL13609481 | 0.81 | CHRNB2 (0.49) | ALDH1A1SMN1; SMN2TSHRLMNAL3MBTL3 | |
| Hydrochloric Acid SCHEMBL29098543 | 0.81 | TSHR (0.58) | ALDH1A1SMN1; SMN2TSHRGABRPGABRD | |
| Hydrochloric Acid SCHEMBL4297704 | 0.80 | CHRNB2 (0.47) | ALDH1A1SMN1; SMN2TSHRLMNAL3MBTL3 | |
| SCHEMBL13609482 | 0.80 | HPGD (0.50) | ALDH1A1SMN1; SMN2TSHRLMNAL3MBTL3 | |
| SCHEMBL4155085 | 0.79 | TSHR (0.61) | ALDH1A1SMN1; SMN2TSHRGABRPGABRD | |
| Hydrochloric Acid SCHEMBL4302489 | 0.79 | HPGD (0.49) | ALDH1A1SMN1; SMN2TSHRLMNAL3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7560569-B2 | (2S,4S)-1-[[(4-carbamoylbicyclo[2.2.2]oct-1-yl)amino]acetyl]-4-fluoropyrrolidine-2-carbonitrile, for treating type II diabetes; increase glucagon-like peptide activity | KYORIN PHARMACEUTICAL CO., LTD (JP) | 2009-07-14 | — | — | US | disclosed |
| US-20070265320-A1 | Bicycloamide Derivative | KYORIN PHARMACEUTICAL CO., LTD (JP) | 2007-11-15 | — | — | US | disclosed |
| EP-1717225-A1 | BICYCLIC AMIDE DERIVATIVES | Kyorin Pharmaceutical Co., Ltd. (JP) | 2006-11-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265320-A1 | Bicycloamide Derivative | DPP4, DPP7, DPP9 | ALDH1A1 71/4885SMN1; SMN2 2259/4885TSHR 2333/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.