SCHEMBL392976

SCHEMBL392976

COC(=O)Cc1ccccc1O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.61
EGFR P00533 3/20 0.49
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.47
TSHR P16473 3/20 0.47
LMNA P02545 1/20 0.47
CYP2D6 P10635 1/20 0.47
HIF1A Q16665 1/20 0.47
HSPA5 P11021 1/20 0.46
ALDH1A1 P00352 2/20 0.46
GAA P10253 1/20 0.46
GFER P55789 1/20 0.46
HSP90AB1 P08238 1/20 0.46
CA12 O43570 2/20 0.45
CA2 P00918 2/20 0.45
NOX4 Q9NPH5 1/20 0.45
ATM Q13315 1/20 0.45
CA1 P00915 1/20 0.45
CA7 P43166 1/20 0.45
CA9 Q16790 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30311288 1.00 AKR1B1 (0.61) AKR1B1EGFRKDM4EMAPTTSHR
Methane SCHEMBL9292057 0.98 AKR1B1 (0.59) AKR1B1EGFRKDM4EMAPTTSHR
Phenol SCHEMBL2808100 0.93 AKR1B1 (0.58) AKR1B1EGFRKDM4EMAPTTSHR
SCHEMBL7606591 0.90 AKR1B1 (0.50) AKR1B1EGFRKDM4EMAPTTSHR
SCHEMBL1554320 0.87 KDM4E (0.53) EGFRKDM4EMAPTTSHRLMNA
SCHEMBL25285645 0.85 IAPP (0.51) AKR1B1EGFRKDM4EMAPTLMNA
SCHEMBL1958849 0.84 AKR1B1 (0.55) AKR1B1KDM4ETSHRLMNAALDH1A1
SCHEMBL2228365 0.83 AKR1B1 (0.65) AKR1B1TSHRCYP2D6HIF1AHSPA5
SCHEMBL29349625 0.83 AKR1B1 (0.65) AKR1B1TSHRCYP2D6HIF1AHSPA5
SCHEMBL21647807 0.83 AKR1B1 (0.44) AKR1B1EGFRKDM4EMAPTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 565 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108997122-B 3-aryl-4-alkoxy benzyl ether derivative and preparation method and application thereof 南方医科大学 2020-12-29 CN claimed
CN-109134765-A A kind of polyisobutene and the graft copolymer of polyisoprene and preparation method thereof 北京化工大学 2019-01-04 CN claimed
CN-108997122-A 3- aryl -4- alkoxy benzyl oxide derivative and its preparation method and application 南方医科大学 2018-12-14 CN claimed
CN-108929226-A A method of preparing benzoyl formic acid ester derivant 广东工业大学 2018-12-04 CN claimed
CN-106606465-A Spot removal cream and preparation method thereof 田川 2017-05-03 CN claimed
US-20050192411-A1 Triazine compounds, polymers comprising triazine structural units, and method GENERAL ELECTRIC CO. 2005-09-01 US claimed
EP-1560817-A1 METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS Reddy US Therapeutics, Inc. (US) 2005-08-10 EP claimed
EP-1423372-A2 TRIAZINE COMPOUNDS, POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND PROCESSES FOR THE PREPARATION OF THESE POLYMERS GENERAL ELECTRIC COMPANY (US) 2004-06-02 EP claimed
WO-2004026844-A1 METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS REDDY US THERAPEUTICS, INC. (US) 2004-04-01 WO claimed
US-20030078347-A1 Triazine compounds, polymers comprising triazine structural units, and method GENERAL ELECTRIC COMPANY 2003-04-24 US claimed
WO-2003024939-A2 TRIAZINE COMPOUNDS POLYMERS COMPRISING TRIAZINE STRUCTURAL UNITS, AND PROCESSES FOR THE PREPARATION OF THESE POLYMERS GENERAL ELECTRIC COMPANY (US) 2003-03-27 WO claimed
US-6538065-B1 Polymerizing a hydroxy-terminated polyester intermediate with a carbonate precursor in a two-phase system comprising an aqueous phase and a water-immiscible organic solvent; use as protective coatings; weatherproof, radiation resistance GENERAL ELECTRIC COMPANY 2003-03-25 US claimed
US-20030050400-A1 METHOD FOR PREPARING COPOLYESTERCARBONATES AND ARTICLES THEREFROM GENERAL ELECTRIC COMPANY 2003-03-13 US claimed
US-6197226-B1 COMPRISING DIPPING RESIN INTO A LIQUID CONTAINING POLAR COMPOUND SELECTED FROM POLAR INORGANIC COMPOUNDS AND POLAR ORGANIC COMPOUNDS AND TINTING RESIN, WHEREIN RESIN IS OBTAINED BY CURING BY POLYMERIZATION A SULFUR CONTAINING COMPOUND MITSUBISHI GAS CHEMICAL COMPANY (JP) 2001-03-06 US claimed
US-5034493-A Comprising the reaction product obtained by heating a mixture of a zinc carboxylate, a carboxylic anhydride aknd a phenol or glycidyl ether or ester; colorless; storage stability; fast c uring; optics NEW JAPAN CHEMICAL CO., LTD. (JP) 1991-07-23 US claimed
US-20260144743-A1 COMPOUNDS TMEM16A LIMITED (GB) 2026-05-28 US disclosed
EP-4714961-A2 PRODRUG MODULATORS OF THE INTEGRATED STRESS PATHWAY Calico Life Sciences LLC (US) 2026-03-25 EP disclosed
EP-0168467-A1 NOVEL ARYLACETIC ACID DERIVATIVES PHARMACIA AB (SE) 1986-01-22 EP disclosed
WO-1985003287-A1 NOVEL ARYLACETIC ACID DERIVATIVES PHARMACIA AB (SE) 1985-08-01 WO disclosed
EP-0150166-A1 Novel arylacitic acid derivatives PHARMACIA AB (SE) 1985-07-31 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144743-A1 COMPOUNDS CACNA1E, TMEM109, CACNA1C AKR1B1 1457/4885EGFR 1775/4885KDM4E 3794/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.