Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4740341 | 0.97 | RAB9A (0.39) | BDKRB1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL4740581 | 0.89 | PDE3B (0.41) | RAB9ASMN1; SMN2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL4741483 | 0.79 | OPRK1 (0.38) | SMN1; SMN2L3MBTL1KMT2AHPGDKDM4E | |
| SCHEMBL4740254 | 0.78 | RAB9A (0.41) | RAB9ASMN1; SMN2ALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL4165173 | 0.77 | OPRK1 (0.35) | BDKRB1SMN1; SMN2ALDH1A1MAPK1HPGD | |
| SCHEMBL4805982 | 0.75 | OPRK1 (0.35) | KMT2A | |
| SCHEMBL3934824 | 0.74 | GAA (0.43) | RAB9ASMN1; SMN2ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL4784194 | 0.74 | BDKRB1 (0.38) | BDKRB1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL17185106 | 0.73 | BDKRB1 (0.48) | BDKRB1RAB9ASMN1; SMN2ALDH1A1MAPK1 | |
| SCHEMBL4742022 | 0.72 | OPRK1 (0.39) | ALDH1A1L3MBTL1KMT2AHPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011627-A1 | PYRIDINE COMPOUNDS AND THEIR USE AS P2Y12 ANTAGONISTS | ASTRAZENECA AB (SE) | 2009-01-22 | — | — | WO | disclosed |
| US-20090018166-A1 | New Pyridine Analogues X 161 | ASTRAZENECA AB (SE) | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018166-A1 | New Pyridine Analogues X 161 | P2RY12, P2RY11, P2RY1 | BDKRB1 150/4885RAB9A 1749/4885SMN1; SMN2 3485/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.