SCHEMBL3930440

SCHEMBL3930440

NCCC[Si](c1ccccc1)(c1ccccc1)c1ccc([Si](CCCN)(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.41
HTR2A P28223 3/20 0.40
HRH1 P35367 3/20 0.40
KIF11 P52732 4/20 0.39
LOXL2 Q9Y4K0 2/20 0.36
CYP2A6 P11509 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TAAR1 Q96RJ0 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21748441 0.79 MAOA (0.43) MAOAHTR2AHRH1KIF11LOXL2
SCHEMBL10402043 0.77 CALM1 (0.35) HTR2AHRH1LOXL2TAAR1
SCHEMBL24433798 0.76 MAOA (0.40) MAOAHTR2AHRH1KIF11LOXL2
SCHEMBL10611414 0.76 MAOA (0.40) MAOAHTR2AHRH1KIF11LOXL2
SCHEMBL4533823 0.76 MAOA (0.40) MAOAHTR2AHRH1KIF11LOXL2
SCHEMBL3865502 0.76 MGAM (0.40) MAOAHTR2AHRH1KIF11LOXL2
SCHEMBL3230668 0.74 KDM4E (0.33)
SCHEMBL7139123 0.74 HDAC3 (0.39)
SCHEMBL10629120 0.74 TDP1 (0.37)
SCHEMBL8986065 0.74 TDP1 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8075824-B2 Polyimide film made of multicomponent polyimide and process of producing the same UBE INDUSTRIES, LTD. (JP) 2011-12-13 US disclosed
US-20090258211-A1 POLYIMIDE FILM MADE OF MULTICOMPONENT POLYIMIDE AND PROCESS OF PRODUCING THE SAME UBE INDUSTRIES, LTD. (JP) 2009-10-15 US disclosed