⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3921708 | 0.97 | KDM1A (0.39) | — | |
| SCHEMBL6039745 | 0.97 | KDM1A (0.39) | — | |
| SCHEMBL3929519 | 0.92 | — | — | |
| SCHEMBL3921050 | 0.80 | — | — | |
| SCHEMBL7040220 | 0.77 | — | — | |
| SCHEMBL9693129 | 0.76 | CA2 (0.44) | — | |
| SCHEMBL140259 | 0.76 | CA2 (0.44) | — | |
| SCHEMBL23961848 | 0.76 | SMN1; SMN2 (0.32) | — | |
| SCHEMBL31532956 | 0.75 | PAOX (0.39) | — | |
| Hydrochloric Acid SCHEMBL28130617 | 0.75 | SMOX (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7485421-B2 | Polyamide-oligonucleotide derivatives, their preparation and use | HOECHST GMBH (DE) | 2009-02-03 | — | — | US | disclosed |
| EP-1113021-B1 | Polyamide-oligonucleotide derivatives, their production and use | SANOFI AVENTIS DEUTSCHLAND (DE) | 2006-08-09 | — | — | EP | disclosed |
| WO-2006038001-A1 | AMINOPYRIMIDINE DERIVATIVES AS JNK INHIBITORS | CELLTECH R & D LIMITED (GB) | 2006-04-13 | — | — | WO | disclosed |
| US-6919441-B2 | Polyamide-oligonucleotide derivatives, their preparation and use | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-07-19 | — | — | US | disclosed |
| US-20050026817-A1 | Polyamide-oligonucleotide derivatives, their preparation and use | AVENTIS PHARMA DEUTSCHLAND GMBH (US) | 2005-02-03 | — | — | US | disclosed |
| EP-0672677-B1 | Polyamide-oligonucleotide derivatives, their production and use | AVENTIS PHARMA GMBH (DE) | 2002-07-03 | — | — | EP | disclosed |
| EP-1113021-A2 | Polyamide-oligonucleotide derivatives, their production and use | Aventis Pharma Deutschland GmbH (DE) | 2001-07-04 | — | — | EP | disclosed |
| EP-0672677-A2 | Polyamide-oligonucleotide derivatives, their production and use | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-20 | — | — | EP | disclosed |