Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | HPGD | P15428 | 4/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.61 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.61 |
| ▸ | AR | P10275 | 2/20 | 0.55 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.42 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.41 |
| ▸ | ITGAL | P20701 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635636 | 0.87 | AR (0.64) | MEN1KMT2AALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL3930889 | 0.82 | AR (0.58) | MEN1KMT2AHSD17B10ALDH1A1HPGD | |
| Fenticlor SCHEMBL29729454 | 0.78 | HSD17B10 (1.00) | MEN1KMT2AHSD17B10ALDH1A1HPGD | |
| Fenticlor SCHEMBL23276 | 0.78 | HSD17B10 (1.00) | MEN1KMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL3938850 | 0.76 | AR (0.49) | MEN1KMT2AALDH1A1HPGDCYP3A4 | |
| Fenticlor SCHEMBL2898956 | 0.76 | HSD17B10 (0.95) | MEN1KMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL4521462 | 0.76 | HPGD (0.56) | MEN1KMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL1332588 | 0.74 | PTGDR2 (0.56) | CYP2C9ARTSHRMAPT | |
| Fenticlor SCHEMBL8863189 | 0.74 | HSD17B10 (0.91) | MEN1KMT2AHSD17B10ALDH1A1HPGD | |
| SCHEMBL407449 | 0.74 | TSHR (0.50) | HSD17B10ARTMPRSS4P2RX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007502806-A | — | — | 2007-02-15 | — | — | JP | claimed |
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | claimed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | claimed |
| EP-1660431-B1 | PHENOXYACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | disclosed |