Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.58 |
| ▸ | ITGB2 | P05107 | 5/20 | 0.45 |
| ▸ | ICAM1 | P05362 | 5/20 | 0.45 |
| ▸ | ITGAL | P20701 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | USP7 | Q93009 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RHEB | Q15382 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
| ▸ | FLT4 | P35916 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7635636 | 0.87 | AR (0.64) | ARITGB2ICAM1ITGALMAOA | |
| SCHEMBL3930893 | 0.82 | MEN1 (0.61) | ARITGB2ICAM1ITGALMAOA | |
| SCHEMBL3938850 | 0.76 | AR (0.49) | ARITGB2ICAM1ITGALUSP7 | |
| SCHEMBL1332588 | 0.74 | PTGDR2 (0.56) | ARMAPTCYP2C9 | |
| SCHEMBL9087127 | 0.74 | VCAM1 (0.48) | ARMAOAMAOBMAPTFLT1 | |
| SCHEMBL694015 | 0.73 | SLC6A2 (0.48) | ARITGB2ICAM1ITGALMAOA | |
| SCHEMBL721330 | 0.71 | TRPV4 (0.43) | ARMAOAMAOBMEN1KMT2A | |
| SCHEMBL4440433 | 0.71 | AR (0.60) | ARITGB2ICAM1ITGALMAOA | |
| SCHEMBL14378077 | 0.71 | AR (0.65) | ARMAOAMAOBMEN1KMT2A | |
| SCHEMBL20755296 | 0.71 | AR (0.56) | ARMAOAMAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007502806-A | — | — | 2007-02-15 | — | — | JP | claimed |
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | claimed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | claimed |
| EP-1660431-B1 | PHENOXYACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2009-04-01 | — | — | EP | disclosed |
| EP-1660431-A2 | PHENOXYACETIC ACID DERIVATIVES | Astrazeneca AB (SE) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005018529-A2 | PHENOXIACETIC ACID DERIVATIVES | ASTRAZENECA AB (SE) | 2005-03-03 | — | — | WO | disclosed |