Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.67 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.66 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.65 |
| ▸ | PTPRC | P08575 | 1/20 | 0.65 |
| ▸ | PTPRF | P10586 | 1/20 | 0.65 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.65 |
| ▸ | PTPA | Q15257 | 1/20 | 0.65 |
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.63 |
| ▸ | HPGD | P15428 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3933219 | 0.93 | LMNA (0.70) | LMNAMAPTMEN1KMT2AALOX12 | |
| SCHEMBL21247167 | 0.89 | LMNA (0.81) | LMNAMAPTMEN1KMT2AALOX12 | |
| SCHEMBL21247385 | 0.87 | TP53 (0.72) | LMNAMAPTMEN1KMT2AALOX12 | |
| SCHEMBL3931523 | 0.86 | PTPN1 (0.78) | LMNAMAPTMEN1KMT2AALOX12 | |
| SCHEMBL3931626 | 0.84 | LMNA (0.67) | LMNAMAPTMEN1KMT2AALOX12 | |
| SCHEMBL13962634 | 0.82 | LMNA (0.72) | LMNAMAPTMEN1KMT2AALOX12 | |
| SCHEMBL21247131 | 0.80 | PTPN1 (0.65) | LMNAMAPTMEN1KMT2AALOX12 | |
| SCHEMBL21248149 | 0.80 | HPGD (0.62) | LMNAMAPTMEN1KMT2AALOX12 | |
| SCHEMBL3934240 | 0.79 | LMNA (0.67) | LMNAMAPTMEN1KMT2AALOX12 | |
| SCHEMBL13926869 | 0.79 | MEN1 (0.58) | MAPTMEN1KMT2ASMN1; SMN2THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
| WO-2009011850-A2 | NOVEL THERAPEUTIC COMPOUNDS | ABBOTT LABORATORIES (US) | 2009-01-22 | — | — | WO | disclosed |
| WO-2009011850-A2 | NOVEL THERAPEUTIC COMPOUNDS | ABBOTT LABORATORIES (US) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | MAP3K20, RPS6KB1, MAP3K1 | LMNA 3011/4885MAPT 3755/4885MEN1 3233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.