Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.65 |
| ▸ | PTPRC | P08575 | 2/20 | 0.65 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.65 |
| ▸ | PTPA | Q15257 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 8/20 | 0.62 |
| ▸ | TP53 | P04637 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | PTPRF | P10586 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21247385 | 0.86 | TP53 (0.72) | PTPN1PTPRCPTPN2PTPAMAPT | |
| SCHEMBL21247173 | 0.86 | MEN1 (0.64) | MEN1KMT2A | |
| SCHEMBL21247167 | 0.84 | LMNA (0.81) | PTPN1PTPRCPTPN2PTPAMAPT | |
| SCHEMBL3933219 | 0.83 | LMNA (0.70) | PTPN1PTPRCPTPN2PTPAMAPT | |
| SCHEMBL3931523 | 0.81 | PTPN1 (0.78) | PTPN1PTPRCPTPN2PTPAMAPT | |
| SCHEMBL21248149 | 0.81 | HPGD (0.62) | PTPN1PTPRCPTPN2PTPAMAPT | |
| SCHEMBL3629109 | 0.80 | MAPT (0.72) | PTPN1PTPRCPTPN2PTPAMAPT | |
| SCHEMBL3627300 | 0.80 | MAPT (0.72) | PTPN1PTPRCPTPN2PTPAMAPT | |
| SCHEMBL3931354 | 0.80 | LMNA (0.67) | PTPN1PTPRCPTPN2PTPAMAPT | |
| SCHEMBL13962634 | 0.79 | LMNA (0.72) | PTPN1PTPRCPTPN2PTPAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | ENYO PHARMA (FR) | 2023-12-12 | — | — | US | disclosed |
| EP-3749649-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO Pharma (FR) | 2020-12-16 | — | — | EP | disclosed |
| US-20200369655-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2020-11-26 | — | — | US | disclosed |
| WO-2019154953-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | ENYO PHARMA (FR) | 2019-08-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200369655-A1 | NON-FUSED THIOPHENE DERIVATIVES AND THEIR USES | FTH1, SLC40A1, FECH | PTPN1 129/4885PTPRC 694/4885PTPN2 136/4885 |
| US-11840527-B2 | Non-fused thiophene derivatives and their uses | FTH1, SLC40A1, FECH | PTPN1 129/4885PTPRC 694/4885PTPN2 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.