Dihydrokaempferol

Dihydrokaempferol

SCHEMBL2036629

O=C1c2c(O)cc(O)cc2O[C@H](c2ccc(O)cc2)[C@H]1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.80
MEN1 O00255 4/20 0.80
KMT2A Q03164 4/20 0.80
MAPT P10636 4/20 0.80
HSD17B10 Q99714 4/20 0.80
ALOX15 P16050 4/20 0.80
ALOX12 P18054 3/20 0.80
RECQL P46063 2/20 0.80
SOST Q9BQB4 2/20 0.80
POLB P06746 2/20 0.80
CYP1A2 P05177 2/20 0.80
KDM4E B2RXH2 2/20 0.80
GAA P10253 2/20 0.80
HIF1A Q16665 2/20 0.80
NFKB1 P19838 1/20 0.80
MAPK1 P28482 1/20 0.80
SYNJ2 O15056 1/20 0.74
APP P05067 1/20 0.74
XDH P47989 1/20 0.66
CBS P35520 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dihydrokaempferol SCHEMBL31026899 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL3437565 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL29454736 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL13354175 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL39319 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL29367287 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL3438673 1.00 CYP3A4 (0.80) CYP3A4MEN1KMT2AMAPTHSD17B10
Dihydrokaempferol SCHEMBL31547241 0.93 MAPT (0.70) CYP3A4MEN1KMT2AMAPTHSD17B10
Pinobaksin SCHEMBL14461145 0.91 MAPT (0.75) CYP3A4MEN1KMT2AMAPTHSD17B10
Pinobaksin SCHEMBL1045054 0.91 MAPT (0.75) CYP3A4MEN1KMT2AMAPTHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 443 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4627099-A2 PROCESS FOR MAKING FLAVANONE DERIVATIVES Firmenich SA (CH) 2025-10-08 EP claimed
US-20240390445-A1 METHOD OF TREATING CANCER Native Ingredients And Health Research Organisation Pty Ltd (AU) 2024-11-28 US claimed
EP-4408196-A1 A METHOD OF TREATING CANCER Native Ingredients And Health Research Organisation Pty Ltd (AU) 2024-08-07 EP claimed
WO-2024115469-A2 PROCESS FOR MAKING FLAVANONE DERIVATIVES FIRMENICH SA (CH) 2024-06-06 WO claimed
US-20230233513-A1 TAXIFOLIN FORMULATION COMPRISING THIAMINE EVANIUM HEALTHCARE GMBH (DE) 2023-07-27 US claimed
WO-2023049970-A1 A METHOD OF TREATING CANCER Native Ingredients And Health Research Organisation Pty Ltd (AU) 2023-04-06 WO claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
EP-4135656-A1 TAXIFOLIN FORMULATION COMPRISING THIAMINE Evanium Healthcare GmbH (DE) 2023-02-22 EP claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
US-20220088199-A1 METHOD FOR PROTECTING GLYCEROL ALKYL ETHERS FROM OXIDATION SACHEM, INC. 2022-03-24 US claimed
EP-2572713-A1 Extracts and isolated flavonoids from Euphorbia cuneata useful as anti-ulcer agents King Saud University (SA) 2013-03-27 EP claimed
CN-102459215-A 3- (4-aminophenyl) -2-furancarboxylic acid derivatives and pharmaceutically acceptable salts thereof DAINIPPON SUMITOMO PHARMA CO 2012-05-16 CN claimed
EP-1395539-B1 A METHOD FOR ISOLATING PHENOLIC SUBSTANCES OR JUVABIONES FROM WOOD COMPRISING KNOTWOOD ARBONOVA AB OY (FI) 2009-04-22 EP claimed
CN-101336978-A Extraction method of total flavone of Hovenia dulcisThunb UNIV NORTHWEST SCI TECH AGRI (CN) 2009-01-07 CN claimed
CN-1553887-A Method for separating phenolic substances or juvabiones from wood containing nodular wood �����ᡤ����ķ��ķ 2004-12-08 CN claimed
US-20040199032-A1 Method for isolating phenolic substances or javabiones from wood comprising knotwood HOLMBOM BJARNE (FI) 2004-10-07 US claimed
EP-1395539-A1 A METHOD FOR ISOLATING PHENOLIC SUBSTANCES OR JUVABIONES FROM WOOD COMPRISING KNOTWOOD Holmbom, Bjarne (FI) 2004-03-10 EP claimed
WO-2002098830-A1 A METHOD FOR ISOLATING PHENOLIC SUBSTANCES OR JUVABIONES FROM WOOD COMPRISING KNOTWOOD HOLMBOM BJARNE (FI) 2002-12-12 WO claimed
EP-0719554-A1 Chondroprotective flavonoids Kureha Chemical Industry Co., Ltd. (JP) 1996-07-03 EP claimed
EP-0633022-A2 Chondroprotective flavones KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-01-11 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB CYP3A4 3571/4885MEN1 1711/4885KMT2A 4742/4885
US-20220088199-A1 METHOD FOR PROTECTING GLYCEROL ALKYL ETHERS FROM OXIDATION GK, ABHD10, CBR3 CYP3A4 308/4885MEN1 3660/4885KMT2A 2923/4885
US-20230233513-A1 TAXIFOLIN FORMULATION COMPRISING THIAMINE SLC19A2, TTPA, FPGS CYP3A4 1472/4885MEN1 644/4885KMT2A 2582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.