Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | CTSL | P07711 | 5/20 | 0.58 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.57 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.57 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.57 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.57 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.57 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.57 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932008 | 1.00 | GAA (0.67) | GAARAB9ACTSLPTPN1HDAC3 | |
| SCHEMBL28790851 | 0.90 | CTSL (0.71) | GAARAB9ACTSLEPHX2ALDH1A1 | |
| SCHEMBL3927028 | 0.90 | CTSL (0.71) | GAARAB9ACTSLEPHX2ALDH1A1 | |
| SCHEMBL6519512 | 0.89 | EPHX2 (0.56) | GAARAB9ACTSLPTPN1HDAC3 | |
| SCHEMBL27761117 | 0.88 | CTSL (0.62) | GAARAB9ACTSLHDAC1HDAC6 | |
| SCHEMBL1784498 | 0.87 | CTSL (0.62) | GAARAB9ACTSLCA2ALDH1A1 | |
| SCHEMBL1796825 | 0.87 | CTSL (0.62) | GAARAB9ACTSLCA2ALDH1A1 | |
| SCHEMBL3935180 | 0.87 | CTSL (0.62) | GAARAB9ACTSLCA2ALDH1A1 | |
| SCHEMBL30064651 | 0.87 | CTSL (0.62) | GAARAB9ACTSLCA2ALDH1A1 | |
| SCHEMBL9461988 | 0.87 | PTPN1 (0.73) | GAARAB9APTPN1HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1691199-B1 | METHOD OF PREDICTING SPOT FORMATION ON THE SKIN WITH THE USE OF SPOT SITE-ACCELERATING GENES AS INDICATION AND METHOD OF SCREENING INHIBITOR FOR SPOT FORMATION ON THE SKIN | SHISEIDO CO LTD (JP) | 2009-04-01 | — | — | EP | disclosed |
| EP-1691199-A1 | METHOD OF PREDICTING SPOT FORMATION ON THE SKIN WITH THE USE OF SPOT SITE-ACCELERATING GENES AS INDICATION AND METHOD OF SCREENING INHIBITOR FOR SPOT FORMATION ON THE SKIN | SHISEIDO COMPANY LIMITED (JP) | 2006-08-16 | — | — | EP | disclosed |