Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14380399 | 0.88 | MEN1 (0.42) | STING1ALDH1A1CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL18427307 | 0.87 | PIN1 (0.38) | ALDH1A1HIF1AMEN1KMT2AAPP | |
| SCHEMBL5265501 | 0.87 | PIN1 (0.38) | ALDH1A1HIF1AMEN1KMT2AAPP | |
| SCHEMBL5268318 | 0.87 | PIN1 (0.38) | ALDH1A1HIF1AMEN1KMT2AAPP | |
| SCHEMBL3669336 | 0.85 | PIN1 (0.39) | ALDH1A1HIF1AMEN1KMT2AAPP | |
| SCHEMBL3668993 | 0.85 | PIN1 (0.39) | ALDH1A1HIF1AMEN1KMT2AAPP | |
| SCHEMBL5265280 | 0.83 | PIN1 (0.36) | STING1ALDH1A1HIF1AAPPEGFR | |
| SCHEMBL5265555 | 0.83 | PIN1 (0.36) | STING1ALDH1A1HIF1AAPPEGFR | |
| SCHEMBL5698022 | 0.81 | MEN1 (0.42) | STING1ALDH1A1CYP3A4MAPK1SMN1; SMN2 | |
| SCHEMBL5620180 | 0.81 | MEN1 (0.42) | STING1ALDH1A1CYP3A4MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7507831-B2 | Tetra- and penta-o-benzyl-protected, C-4 activated-epicatechin and -catechin monomers and processes for their preparation and use | MARS, INC. | 2009-03-24 | — | — | US | disclosed |
| US-20070276147-A1 | Synthesis of Oligomeric Epicatechin- and Catechin-Derived Procyanidins | KOZIKOWSKI ALAN P | 2007-11-29 | — | — | US | disclosed |
| US-7244855-B2 | Synthesis of oligomeric epicatechin and catechin-derived procyanidins | MARS, INC. | 2007-07-17 | — | — | US | disclosed |
| US-20060173198-A1 | Synthesis of dimeric, trimeric, tetrameric, pentameric, and higher oligomeric epicatechin-derived procyanidins having 4beta,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest | KOZIKOWSKI ALAN P | 2006-08-03 | — | — | US | disclosed |
| US-7067679-B2 | Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest | MARS, INC. | 2006-06-27 | — | — | US | disclosed |
| US-20050020512-A1 | Synthesis of oligomeric epicatechin and catechin-derived procyanidins | MARS, INCORPORATED | 2005-01-27 | — | — | US | disclosed |
| US-20040116718-A1 | Synthesis of dimeric, trimeric, tetrameric pentameric, and higher oligomeric epicatechin-derived procyanidins having 4beta,8-interflavan linkages and their use to inhibit cancer cell growth through cell cycle arrest | MARS, INC. | 2004-06-17 | — | — | US | disclosed |