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SCHEMBL5620180

SCHEMBL5620180

CC(=O)OC1c2c(OCc3ccccc3)cc(OCc3ccccc3)cc2OC(c2ccc(O)c(OCc3ccccc3)c2)C1OCc1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.42
▸ KMT2A Q03164 2/20 0.42
▸ MAOB P27338 2/20 0.40
▸ STING1 Q86WV6 1/20 0.39
▸ SIRT1 Q96EB6 1/20 0.39
▸ MCL1 Q07820 2/20 0.37
▸ GAA P10253 2/20 0.37
▸ MAPK10 P53779 1/20 0.37
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ ALDH1A1 P00352 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ MAPK1 P28482 1/20 0.36
▸ PTPN1 P18031 1/20 0.36
▸ ABCB1 P08183 1/20 0.35
▸ BCHE P06276 1/20 0.35
▸ ACHE P22303 1/20 0.35
▸ MAPT P10636 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5698022 1.00 MEN1 (0.42) MEN1KMT2AMAOBSTING1SIRT1
SCHEMBL5620552 0.86 SIRT1 (0.41) MAOBSIRT1MCL1GAAMAPK10
SCHEMBL5523109 0.86 SIRT1 (0.41) MAOBSIRT1MCL1GAAMAPK10
SCHEMBL4620243 0.85 SIRT1 (0.38) MAOBSIRT1MCL1GAAMAPK10
SCHEMBL6690567 0.84 BCHE (0.38) MEN1KMT2AMAOBSIRT1MCL1
SCHEMBL14380399 0.83 MEN1 (0.42) MEN1KMT2AMAOBSTING1SMN1; SMN2
SCHEMBL3932082 0.81 STING1 (0.41) MEN1KMT2AMAOBSTING1SMN1; SMN2
SCHEMBL18427307 0.78 PIN1 (0.38) MEN1KMT2AMAOBALDH1A1BCHE
SCHEMBL5268318 0.78 PIN1 (0.38) MEN1KMT2AMAOBALDH1A1BCHE
SCHEMBL5265501 0.78 PIN1 (0.38) MEN1KMT2AMAOBALDH1A1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7282598-B2 Synthetic methods for preparing procyanidin oligomers MARS, INC. 2007-10-16 — — US disclosed
EP-1175415-B1 SYNTHETIC METHODS FOR PREPARING PROCYANIDIN DIMERS MARS INC (US) 2006-10-18 — — EP disclosed
EP-1686123-A2 Synthetic methods for preparing procyanidin oligomers Mars, Incorporated (US) 2006-08-02 — — EP disclosed
US-7015338-B1 Synthetic methods for preparing procyanidin oligomers MARS INCORPORATED (US) 2006-03-21 — — US disclosed
US-6864377-B2 Synthetic methods for preparing procyanidin oligomers MARS INCORPORATED (US) 2005-03-08 — — US disclosed
US-20040176441-A1 Synthetic methods for preparing procyanidin oligomers MARS INCORPORATED 2004-09-09 — — US disclosed
US-20030114691-A1 Synthetic methods for preparing procyanidin oligomers MARS INCORPORATED 2003-06-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176441-A1 Synthetic methods for preparing procyanidin oligomers C9, NOD2, CASP8 MEN1 1740/4885KMT2A 2915/4885MAOB 827/4885
US-20030114691-A1 Synthetic methods for preparing procyanidin oligomers C9, NOD2, CASP8 MEN1 1740/4885KMT2A 2915/4885MAOB 827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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