SCHEMBL3932111

SCHEMBL3932111

O=S(=O)(c1ccc(F)cc1F)N1CCc2c(ccnc2Nc2cnc3ccccc3c2)C1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FAAH O00519 10/20 0.75
MKNK1 Q9BUB5 10/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3936249 0.93 FAAH (0.72) FAAHMKNK1
SCHEMBL3942409 0.93 FAAH (0.77) FAAHMKNK1
SCHEMBL3934207 0.93 FAAH (0.73) FAAHMKNK1
SCHEMBL3941351 0.92 FAAH (0.74) FAAHMKNK1
SCHEMBL3934462 0.92 FAAH (0.72) FAAHMKNK1
SCHEMBL3935789 0.91 FAAH (0.73) FAAHMKNK1
SCHEMBL3931245 0.90 FAAH (0.74) FAAHMKNK1
SCHEMBL3942437 0.89 FAAH (0.88) FAAH
SCHEMBL3934225 0.88 FAAH (0.72) FAAHMKNK1
SCHEMBL3934243 0.88 FAAH (0.83) FAAHMKNK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009011904-A1 COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF RENOVIS, INC. (US) 2009-01-22 WO disclosed