Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 10/20 | 0.73 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.46 |
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.46 |
| ▸ | ALPL | P05186 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3932111 | 0.93 | FAAH (0.75) | FAAHMKNK1 | |
| SCHEMBL3938676 | 0.92 | FAAH (0.75) | FAAHEPHX2ALPL | |
| SCHEMBL3936249 | 0.91 | FAAH (0.72) | FAAHMKNK1ALPL | |
| SCHEMBL3942409 | 0.91 | FAAH (0.77) | FAAHMKNK1ALPL | |
| SCHEMBL3934474 | 0.90 | FAAH (0.75) | FAAHEPHX2ALPL | |
| SCHEMBL3941351 | 0.89 | FAAH (0.74) | FAAHEPHX2MKNK1 | |
| SCHEMBL3935789 | 0.88 | FAAH (0.73) | FAAHEPHX2MKNK1ALPL | |
| SCHEMBL3935918 | 0.88 | FAAH (0.76) | FAAHEPHX2MKNK1ALPL | |
| SCHEMBL3931245 | 0.88 | FAAH (0.74) | FAAHEPHX2MKNK1 | |
| SCHEMBL3936894 | 0.87 | FAAH (0.79) | FAAHEPHX2ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |