Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.76 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.76 |
| ▸ | MAPT | P10636 | 5/20 | 0.76 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | TSHR | P16473 | 1/20 | 0.76 |
| ▸ | PRKCZ | Q05513 | 11/20 | 0.74 |
| ▸ | HPGD | P15428 | 4/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.57 |
| ▸ | PRKCI | P41743 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1899041 | 0.86 | PRKCZ (0.70) | ALDH1A1HSD17B10MAPTMAPK1TSHR | |
| SCHEMBL8288639 | 0.85 | ALDH1A1 (0.76) | ALDH1A1HSD17B10MAPTMAPK1TSHR | |
| SCHEMBL2182710 | 0.85 | PRKCZ (1.00) | ALDH1A1HSD17B10MAPTMAPK1TSHR | |
| SCHEMBL3995640 | 0.85 | ALDH1A1 (0.76) | ALDH1A1HSD17B10MAPTMAPK1TSHR | |
| SCHEMBL688523 | 0.85 | PRKCZ (1.00) | ALDH1A1HSD17B10MAPTMAPK1TSHR | |
| SCHEMBL690269 | 0.85 | PRKCZ (1.00) | ALDH1A1HSD17B10MAPTMAPK1TSHR | |
| SCHEMBL12271891 | 0.85 | PRKCZ (0.68) | ALDH1A1HSD17B10MAPTMAPK1TSHR | |
| SCHEMBL6927654 | 0.83 | PRKCZ (0.66) | ALDH1A1HSD17B10MAPTMAPK1TSHR | |
| SCHEMBL2369108 | 0.81 | PRKCZ (0.63) | ALDH1A1HSD17B10MAPTMAPK1TSHR | |
| SCHEMBL15940253 | 0.81 | KDM4E (0.56) | ALDH1A1HSD17B10MAPTMAPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
| WO-2009011850-A2 | NOVEL THERAPEUTIC COMPOUNDS | ABBOTT LABORATORIES (US) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | MAP3K20, RPS6KB1, MAP3K1 | ALDH1A1 1426/4885HSD17B10 1621/4885MAPT 3755/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.