Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11415551 | 0.92 | TSHR (0.40) | TSHRKDM4EKMT2AATMRECQL | |
| SCHEMBL3922986 | 0.90 | SIGMAR1 (0.35) | TSHRKDM4EKMT2AATMRECQL | |
| Edetol SCHEMBL2803498 | 0.89 | TSHR (0.39) | TSHRKDM4EKMT2AATMRECQL | |
| Edetol SCHEMBL48412 | 0.89 | TSHR (0.39) | TSHRKDM4EKMT2AATMRECQL | |
| SCHEMBL3929227 | 0.88 | SIGMAR1 (0.34) | TSHRKDM4EKMT2AATMRECQL | |
| SCHEMBL3919959 | 0.88 | SIGMAR1 (0.38) | TSHRKDM4EKMT2APLA2G1BPLA2G2A | |
| SCHEMBL19368375 | 0.86 | TSHR (0.44) | TSHRKDM4EKMT2AATMRECQL | |
| Edetol SCHEMBL8989695 | 0.86 | KDM4E (0.38) | TSHRKDM4EKMT2AATMRECQL | |
| SCHEMBL9785645 | 0.86 | KDM4E (0.38) | TSHRKDM4EKMT2AATMRECQL | |
| Edetol SCHEMBL20942798 | 0.86 | KDM4E (0.38) | TSHRKDM4EKMT2AATMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2878609-B1 | AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND AND POLYISOCYANATE ADHESIVE COMPOSITION CONTAINING AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND | TOSOH CORP (JP) | 2019-06-05 | — | — | EP | claimed |
| US-9777199-B2 | Amine catalyst for curing polyisocyanate compound and polyisocyanate adhesive composition containing amine catalyst for curing polyisocyanate compound | TOSOH CORPORATION (JP) | 2017-10-03 | — | — | US | claimed |
| US-20150203727-A1 | AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND AND POLYISOCYANATE ADHESIVE COMPOSITION CONTAINING AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND | TOSOH CORPORATION (JP) | 2015-07-23 | — | — | US | claimed |
| EP-2878609-A1 | AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND AND POLYISOCYANATE ADHESIVE COMPOSITION CONTAINING AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND | Tosoh Corporation (JP) | 2015-06-03 | — | — | EP | claimed |
| EP-2878609-B1 | AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND AND POLYISOCYANATE ADHESIVE COMPOSITION CONTAINING AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND | TOSOH CORP (JP) | 2019-06-05 | — | — | EP | disclosed |
| US-9777199-B2 | Amine catalyst for curing polyisocyanate compound and polyisocyanate adhesive composition containing amine catalyst for curing polyisocyanate compound | TOSOH CORPORATION (JP) | 2017-10-03 | — | — | US | disclosed |
| US-20150203727-A1 | AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND AND POLYISOCYANATE ADHESIVE COMPOSITION CONTAINING AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND | TOSOH CORPORATION (JP) | 2015-07-23 | — | — | US | disclosed |
| EP-2878609-A1 | AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND AND POLYISOCYANATE ADHESIVE COMPOSITION CONTAINING AMINE CATALYST FOR CURING POLYISOCYANATE COMPOUND | Tosoh Corporation (JP) | 2015-06-03 | — | — | EP | disclosed |
| US-7572837-B2 | Process for the production of flexible polyurethane foams | TOSOH CORPORATION (JP) | 2009-08-11 | — | — | US | disclosed |
| US-20030144371-A1 | Catalyzing the copolymerization in presence of imidazole compounds, free of tin comound, forming polyetherurethane copolymers | TOSOH CORPORATION (JP) | 2003-07-31 | — | — | US | disclosed |
| EP-1312630-A1 | Process for the production of flexible polyurethane foams | Tosoh Corporation (JP) | 2003-05-21 | — | — | EP | disclosed |
| US-5128408-A | Quaternized amino polyurethane- or polyurethaneurea-polysiloxanes treated with heparin | TOYO BOSEKI KABUSHIKI KAISHA (JP) | 1992-07-07 | — | — | US | disclosed |
| US-4374219-A | STABILIZERS FOR POLYMERS | CIBA-GEIGY CORPORATION (US) | 1983-02-15 | — | — | US | disclosed |
| US-4318845-A | STABILIZERS | CIBA-GEIGY CORPORATION (US) | 1982-03-09 | — | — | US | disclosed |