Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL28563702 | 0.79 | TSHR (0.43) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL396541 | 0.76 | POLB (0.35) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL7184008 | 0.74 | ALDH1A1 (0.35) | POLBTDP1TSHRGAAALDH1A1 | |
| Toluene SCHEMBL27784195 | 0.73 | TDP1 (0.45) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL1563224 | 0.72 | TSHR (0.50) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL15276 | 0.70 | TSHR (0.55) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL5446210 | 0.70 | TSHR (0.55) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL15910586 | 0.70 | POLB (0.54) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL15910782 | 0.70 | POLB (0.50) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL221578 | 0.70 | TSHR (0.50) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110697-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-8101789-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| US-20100041909-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | disclosed |
| US-20100029972-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-04 | — | — | US | disclosed |