Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | CA2 | P00918 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393260 | 0.76 | POLB (0.38) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL7639170 | 0.73 | TSHR (0.49) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL7184008 | 0.71 | ALDH1A1 (0.35) | POLBTDP1TSHR | |
| SCHEMBL7638067 | 0.71 | TSHR (0.53) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL5702062 | 0.69 | TSHR (0.44) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL20555059 | 0.69 | TSHR (0.50) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL4753653 | 0.68 | TSHR (0.45) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL5701772 | 0.68 | TSHR (0.45) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL397026 | 0.68 | TSHR (0.45) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL4964369 | 0.67 | TSHR (0.55) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8110697-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-02-07 | — | — | US | disclosed |
| US-8101789-B2 | Method for the production of polymerizable silicones | WACKER CHEMIE AG (DE) | 2012-01-24 | — | — | US | disclosed |
| US-20100041909-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-18 | — | — | US | disclosed |
| US-20100029972-A1 | METHOD FOR THE PRODUCTION OF POLYMERIZABLE SILICONES | WACKER CHEMIE AG (DE) | 2010-02-04 | — | — | US | disclosed |