Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.83 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3940445 | 0.94 | FAAH (0.84) | FAAHEPHX2ALDH1A1KDM4ELMNA | |
| SCHEMBL3941343 | 0.91 | FAAH (0.86) | FAAHEPHX2ALDH1A1KDM4ELMNA | |
| SCHEMBL3941135 | 0.91 | FAAH (1.00) | FAAHALDH1A1LMNAHTTMEN1 | |
| SCHEMBL3939389 | 0.90 | FAAH (0.83) | FAAHALDH1A1LMNAHTTMEN1 | |
| SCHEMBL3939612 | 0.90 | FAAH (0.83) | FAAHALDH1A1LMNAHTTMEN1 | |
| SCHEMBL3934243 | 0.90 | FAAH (0.83) | FAAHALDH1A1LMNAHTTMEN1 | |
| SCHEMBL3942978 | 0.89 | FAAH (0.86) | FAAHALDH1A1LMNAHTTGAA | |
| SCHEMBL3932545 | 0.89 | FAAH (0.79) | FAAHALPLMAPTMKNK1AKR1C3 | |
| SCHEMBL3935918 | 0.89 | FAAH (0.76) | FAAHEPHX2ALDH1A1KDM4ELMNA | |
| SCHEMBL3930701 | 0.88 | FAAH (0.86) | FAAHALDH1A1KDM4ELMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |