Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.76 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3936835 | 0.90 | FAAH (0.80) | FAAHEPHX2ALDH1A1LMNAMAPK1 | |
| SCHEMBL3940445 | 0.89 | FAAH (0.84) | FAAHEPHX2ALDH1A1LMNAMAPK1 | |
| SCHEMBL3932908 | 0.89 | FAAH (0.83) | FAAHEPHX2ALDH1A1LMNAMAPK1 | |
| SCHEMBL3941343 | 0.89 | FAAH (0.86) | FAAHEPHX2ALDH1A1LMNAMAPK1 | |
| SCHEMBL3934207 | 0.88 | FAAH (0.73) | FAAHEPHX2ALPLMKNK1 | |
| SCHEMBL3938676 | 0.88 | FAAH (0.75) | FAAHEPHX2ALDH1A1ALPLKDM4E | |
| SCHEMBL3934474 | 0.88 | FAAH (0.75) | FAAHEPHX2ALDH1A1LMNAMAPK1 | |
| SCHEMBL4017126 | 0.87 | FAAH (0.72) | FAAHEPHX2ALDH1A1LMNAMAPK1 | |
| SCHEMBL3936894 | 0.87 | FAAH (0.79) | FAAHEPHX2ALDH1A1LMNAMAPK1 | |
| SCHEMBL3941135 | 0.86 | FAAH (1.00) | FAAHALDH1A1LMNAMAPK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |