Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27984159 | 0.87 | ALDH1A1 (0.53) | ALDH1A1TDP1ADRA2BPTGS1GAA | |
| SCHEMBL6557214 | 0.85 | CALM1 (0.52) | CALM1SMN1; SMN2ALDH1A1LOXL2MAPT | |
| SCHEMBL27640492 | 0.84 | CALM1 (0.42) | CALM1HPGDSMN1; SMN2ALDH1A1LOXL2 | |
| Hydrochloric Acid SCHEMBL2873364 | 0.83 | CALM1 (0.50) | CALM1SMN1; SMN2ALDH1A1LOXL2MAPT | |
| Alcohol SCHEMBL28228430 | 0.83 | ALDH1A1 (0.48) | ALDH1A1TDP1ADRA2BPTGS1LTA4H | |
| SCHEMBL1498780 | 0.78 | CALM1 (0.55) | CALM1SMN1; SMN2ALDH1A1LOXL2MAPT | |
| SCHEMBL7669757 | 0.78 | CALM1 (0.44) | CALM1HPGDSMN1; SMN2ALDH1A1LOXL2 | |
| SCHEMBL9816698 | 0.78 | DPP4 (0.50) | CALM1ALDH1A1MAPTPOLBKDM4E | |
| SCHEMBL7033288 | 0.78 | HPGD (0.49) | CALM1HPGDSMN1; SMN2L3MBTL1CYP1A2 | |
| SCHEMBL398862 | 0.78 | HTR2A (0.48) | CALM1HPGDSMN1; SMN2LOXL2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101655-B2 | Fluorescent dyes and complexes | SMITH GERALD ARTHUR (GB) | 2012-01-24 | — | — | US | disclosed |
| US-20100256399-A1 | FLUORESCENT DYES AND COMPLEXES | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2010-10-07 | — | — | US | disclosed |
| US-7674918-B2 | Fluorescent dyes and complexes | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2010-03-09 | — | — | US | disclosed |
| US-20070238884-A1 | Fluorescent Dyes and Complexes | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2007-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070238884-A1 | Fluorescent Dyes and Complexes | F12, PYM1, ANXA6 | CALM1 2563/4885HPGD 3198/4885SMN1; SMN2 3665/4885 |
| US-20100256399-A1 | FLUORESCENT DYES AND COMPLEXES | F12, ANXA6, PYM1 | CALM1 2294/4885HPGD 2826/4885SMN1; SMN2 3425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.