SCHEMBL3933070

SCHEMBL3933070

CC(=O)CC(=O)Nc1nc2ccccc2s1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 2/20 0.72
ADORA1 P30542 1/20 0.72
ALDH1A1 P00352 5/20 0.70
MAPK1 P28482 2/20 0.69
SMN1; SMN2 Q16637 4/20 0.68
CSNK1D P48730 3/20 0.68
NFKB1 P19838 1/20 0.68
NFKB2 Q00653 1/20 0.68
RELA Q04206 1/20 0.68
POLB P06746 1/20 0.68
RAB9A P51151 7/20 0.67
NPC1 O15118 6/20 0.67
KDM4E B2RXH2 1/20 0.67
HTT P42858 1/20 0.67
ACP1 P24666 1/20 0.66
MAPT P10636 4/20 0.65
MEN1 O00255 3/20 0.65
KMT2A Q03164 3/20 0.65
NCS1 P62166 1/20 0.64
LMNA P02545 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6206186 0.86 RAB9A (0.72) DYRK1AADORA1ALDH1A1MAPK1SMN1; SMN2
SCHEMBL25938107 0.86 CSNK1D (0.69) DYRK1AADORA1ALDH1A1MAPK1SMN1; SMN2
Hydrochloric Acid SCHEMBL25333657 0.85 CSNK1D (0.68) DYRK1AADORA1ALDH1A1MAPK1SMN1; SMN2
SCHEMBL3283083 0.84 DYRK1A (1.00) DYRK1AADORA1ALDH1A1SMN1; SMN2NFKB1
SCHEMBL19771114 0.84 POLB (0.74) DYRK1AADORA1ALDH1A1MAPK1SMN1; SMN2
SCHEMBL7933388 0.83 HDAC3 (0.71) DYRK1AADORA1ALDH1A1MAPK1SMN1; SMN2
SCHEMBL29485043 0.83 DYRK1A (0.69) DYRK1AADORA1ALDH1A1MAPK1SMN1; SMN2
SCHEMBL29485044 0.83 DYRK1A (0.69) DYRK1AADORA1ALDH1A1MAPK1SMN1; SMN2
SCHEMBL29282910 0.83 DYRK1A (0.69) DYRK1AADORA1ALDH1A1MAPK1SMN1; SMN2
SCHEMBL4858014 0.83 CSNK1D (0.69) DYRK1AADORA1ALDH1A1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0138761-B1 PROCESS FOR THE PIGMENTATION OF MACROMOLECULAR ORGANIC MATERIALS CIBA-GEIGY AG (CH) 1989-03-22 EP claimed
EP-0138761-A2 Process for the pigmentation of macromolecular organic materials CIBA-GEIGY AG (CH) 1985-04-24 EP claimed
EP-1344055-A4 MATERIALS FOR ENHANCING STAINING OF BIOPOLYMERS IN MATRICES INVITROGEN CORP (US) 2009-03-25 EP disclosed
US-7144738-B2 Materials for enhancing staining of biopolymers in matrices WHITNEY SCOTT 2006-12-05 US disclosed
US-20060219976-A1 Fluorescent colorant compositions, coloring process and colored articles DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 2006-10-05 US disclosed
EP-1688473-A2 Fluorescent colourant compositions, colouring process and coloured articles Dainichiseika Color & Chemicals Mfg. Co., Ltd. (JP) 2006-08-09 EP disclosed
US-20050170517-A1 Materials for enhancing staining of biopolymers in matrices INVITROGEN CORPORATION (US) 2005-08-04 US disclosed
US-6878551-B2 For proteins/polypeptides within polyacrylamide matrix; mass spectrometry INVITROGEN CORPORATION (US) 2005-04-12 US disclosed
US-20040038418-A1 Materials for enhancing staining of biopolymers in matrices INVITROGEN CORPORATION 2004-02-26 US disclosed
US-6635489-B2 Sensitizing the matrix with heteroaromatic compounds, contacting with reduceable metal salts to stain and detecting INVITROGEN CORPORATION 2003-10-21 US disclosed
EP-1344055-A1 MATERIALS FOR ENHANCING STAINING OF BIOPOLYMERS IN MATRICES INVITROGEN CORPORATION (US) 2003-09-17 EP disclosed
US-20020137222-A1 Materials for enhancing staining of biopolymers in matrices INVITROGEN CORPORATION 2002-09-26 US disclosed
WO-2002042764-A1 MATERIALS FOR ENHANCING STAINING OF BIOPOLYMERS IN MATRICES INVITROGEN CORPORATION (US) 2002-05-30 WO disclosed
EP-0138761-B1 PROCESS FOR THE PIGMENTATION OF MACROMOLECULAR ORGANIC MATERIALS CIBA-GEIGY AG (CH) 1989-03-22 EP disclosed
US-4602961-A MONOAZO BENZOTHIAZOLE DERIVATIVES CIBA-GEIGY CORPORATION (US) 1986-07-29 US disclosed
EP-0138761-A2 Process for the pigmentation of macromolecular organic materials CIBA-GEIGY AG (CH) 1985-04-24 EP disclosed