Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.69 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.69 |
| ▸ | RELA | Q04206 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | ACP1 | P24666 | 1/20 | 0.68 |
| ▸ | NCS1 | P62166 | 1/20 | 0.66 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.65 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.63 |
| ▸ | AURKA | O14965 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206186 | 0.84 | RAB9A (0.72) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL5313704 | 0.84 | CSNK1D (0.69) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL29282910 | 0.84 | DYRK1A (0.69) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL29485043 | 0.84 | DYRK1A (0.69) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| Ethylene SCHEMBL8167289 | 0.84 | CSNK1D (0.69) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL29485044 | 0.84 | DYRK1A (0.69) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL7933388 | 0.84 | HDAC3 (0.71) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| Hydrochloric Acid SCHEMBL25333657 | 0.83 | CSNK1D (0.68) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL3933070 | 0.83 | DYRK1A (0.72) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA | |
| SCHEMBL5070926 | 0.83 | POLB (0.76) | CSNK1DSMN1; SMN2NFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116102546-B | Butyrylcholine esterase and monoamine oxidase B dual inhibitor and application thereof | 浙江海洋大学 | 2025-02-11 | — | — | CN | claimed |
| WO-2024177606-A1 | QUINAZOLINONE DERIVATIVE COMPOUNDS SHOWING ANTI-CANCER ACTIVITY AND THE SYNTHESIS METHODS OF THESE COMPOUNDS | BILECIK SEYH EDEBALI UNIVERSITESI (TR) | 2024-08-29 | — | — | WO | claimed |
| EP-3959200-B1 | NEW TRIAZOLE AND TRIAZOLOTHIADIAZINE DERIVATIVES EXERTING CYTOTOXIC AND APOPTOTIC EFFECTS ON A549 CELLS THROUGH AKT INHIBITION | ANADOLU UNIV (TR) | 2024-03-20 | — | — | EP | claimed |
| CN-116102546-A | Butyrylcholine esterase and monoamine oxidase B dual inhibitor and application thereof | 浙江海洋大学 | 2023-05-12 | — | — | CN | claimed |
| CN-102070564-B | Benzothiazole alkyl xanthate derivative and preparation method and application thereof | UNIV DONGGUAN TECHNOLOGY | 2012-11-21 | — | — | CN | claimed |
| CN-102070564-A | Benzothiazole alkyl xanthate derivative and preparation method and application thereof | UNIV DONGGUAN TECHNOLOGY | 2011-05-25 | — | — | CN | claimed |
| CN-119954794-A | Flavonol derivative containing benzothiazole, and preparation method and application thereof | 贵州大学 | 2025-05-09 | — | — | CN | disclosed |
| CN-116102546-B | Butyrylcholine esterase and monoamine oxidase B dual inhibitor and application thereof | 浙江海洋大学 | 2025-02-11 | — | — | CN | disclosed |
| WO-2024177606-A1 | QUINAZOLINONE DERIVATIVE COMPOUNDS SHOWING ANTI-CANCER ACTIVITY AND THE SYNTHESIS METHODS OF THESE COMPOUNDS | BILECIK SEYH EDEBALI UNIVERSITESI (TR) | 2024-08-29 | — | — | WO | disclosed |
| CN-118063452-A | Benzothiazole or benzoxazole derivative and preparation method and application thereof | 山东大学 | 2024-05-24 | — | — | CN | disclosed |
| CN-117843579-A | Benzo heterocycle coupled catechol derivative and preparation method and application thereof | 暨南大学 | 2024-04-09 | — | — | CN | disclosed |
| US-20240018135-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF | MEDIFRON DBT INC. (KR) | 2024-01-18 | — | — | US | disclosed |
| US-20240018135-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF | MEDIFRON DBT INC. (KR) | 2024-01-18 | — | — | US | disclosed |
| US-20030134827-A1 | Novel lactam metalloprotease inhibitors | DUAN JINGWU (US) | 2003-07-17 | — | — | US | disclosed |
| US-6403632-B1 | CYCLIC AMIDE DERIVATIVE | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2002-06-11 | — | — | US | disclosed |
| EP-1027332-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Du Pont Pharmaceuticals Company (US) | 2000-08-16 | — | — | EP | disclosed |
| US-6057336-A | ANTIINFLAMMATORY AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-05-02 | — | — | US | disclosed |
| EP-0929550-A1 | $i(N)-(BENZOTHIAZOL-2-YL) PIPERIDINE-1-ETHANAMINE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1999-07-21 | — | — | EP | disclosed |
| WO-1999018074-A1 | NOVEL LACTAM METALLOPROTEASE INHIBITORS | Britol-Myers Squibb Pharma Company (US) | 1999-04-15 | — | — | WO | disclosed |
| WO-1998014444-A1 | N-(BENZOTHIAZOL-2-YL) PIPERIDINE-1-ETHANAMINE DERIVATIVES, THEIR PREPARATION AND APPLICATION IN THERAPEUTICS | SYNTHELABO (FR) | 1998-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134827-A1 | Novel lactam metalloprotease inhibitors | ADAM9, ADAM8, ADAM17 | CSNK1D 926/4885SMN1; SMN2 2789/4885NFKB1 1135/4885 |
| US-20240018135-A1 | COMPOUND HAVING INHIBITORY ACTIVITY AGAINST O-GLUSACASE AND USE THEREOF | OGA, OGT, ENGASE | CSNK1D 4503/4885SMN1; SMN2 4435/4885NFKB1 2894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.