Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941900 | 0.88 | MAPT (0.53) | MEN1KMT2AHSD17B10ATMMAPT | |
| SCHEMBL13902144 | 0.84 | RORC (0.57) | MEN1KMT2AHSD17B10ATMMAPT | |
| SCHEMBL3933197 | 0.83 | MAPT (0.52) | MEN1KMT2AHSD17B10ATMMAPT | |
| SCHEMBL3933802 | 0.83 | HSD17B10 (0.69) | MEN1KMT2AHSD17B10ATMMAPT | |
| SCHEMBL3933200 | 0.81 | MAPT (0.52) | MEN1KMT2AHSD17B10ATMMAPT | |
| SCHEMBL3933044 | 0.80 | MAP4K4 (0.61) | MEN1KMT2AHSD17B10ATMMAPT | |
| SCHEMBL3933039 | 0.80 | MAP4K4 (0.61) | MEN1KMT2AHSD17B10ATMMAPT | |
| SCHEMBL3942313 | 0.80 | MAPT (0.54) | MEN1KMT2AHSD17B10ATMMAPT | |
| SCHEMBL13901887 | 0.79 | MAPT (0.52) | HSD17B10MAPTKDM4EHPGDNPC1 | |
| SCHEMBL13901888 | 0.79 | MAPT (0.52) | HSD17B10MAPTKDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | ABBVIE INC. | 2009-03-12 | — | — | US | disclosed |
| WO-2009011850-A2 | NOVEL THERAPEUTIC COMPOUNDS | ABBOTT LABORATORIES (US) | 2009-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069288-A1 | Novel therapeutic compounds | MAP3K20, RPS6KB1, MAP3K1 | MEN1 3233/4885KMT2A 3833/4885HSD17B10 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.