SCHEMBL393346

SCHEMBL393346

N[C@@H](C[C@H](O)C(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.56
SLC1A1 P43005 5/20 0.52
SLC1A3 P43003 5/20 0.50
SLC1A2 P43004 5/20 0.50
PTGS1 P23219 1/20 0.48
SLC7A11 Q9UPY5 1/20 0.48
GRIK1 P39086 4/20 0.46
GRIK2 Q13002 4/20 0.46
GGT1 P19440 2/20 0.46
GRM1 Q13255 1/20 0.46
GRM2 Q14416 1/20 0.46
OR51E2 Q9H255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4254400 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL4947418 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL5819946 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL5823952 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL13746293 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL196983 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL1607862 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL305904 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL13753646 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL3744052 0.84 OR51E2 (0.42) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020006645-A1 Method for producing optically active compound HASHIMOTO SHIN-ICHI (JP) 2002-01-17 US claimed
US-6207427-B1 ALLOWING RECOMBINANT MICROORGANISM CARRYING RECOMBINANT DNA HARBORING (S)-4-HYDROXY-2-KETOGLUTARIC ACID ALDOLASE GENE TO ACT ON SUGAR AND GLYOXYLIC ACID IN AN AQUEOUS MEDIUM, AND COLLECTING OPTICALLY ACTIVE (S)-4-HYDROXY-2-KETOGLUTARIC ACID KYOWA HAKKO KOGYO, LTD. (JP) 2001-03-27 US claimed
EP-0692539-B1 Process for producing an optically active gamma-hydroxy-L-glutamic acid KYOWA HAKKO KOGYO KK (JP) 1999-09-22 EP claimed
EP-0884390-A2 Method for producing an optically active compound KYOWA HAKKO KOGYO CO., LTD. (JP) 1998-12-16 EP claimed
US-5643769-A Process for producing an optically active γ-hydroxy-L-glutamic acid KYOWA HAKKO KOGYO CO., LTD. (JP) 1997-07-01 US claimed
EP-0692539-A2 Process for producing an optically active gamma-hydroxy-L-glutamic acid KYOWA HAKKO KOGYO CO., LTD. (JP) 1996-01-17 EP claimed
JP-11056379-A None JP disclosed
EP-4181781-B1 BREATH-BASED THERAPEUTIC DRUG MONITORING METHOD UNIV KINDERSPITAL BEIDER BASEL (CH) 2026-05-20 EP disclosed
US-20230277125-A1 BREATH-BASED THERAPEUTIC DRUG MONITORING METHOD UNIVERSITÄTS-KINDERSPITAL BEIDER BASEL (CH) 2023-09-07 US disclosed
US-20220142948-A1 COMPOSITIONS AND METHODS FOR MODULATING METABOLIC REGULATORS OF T CELL PATHOGENICITY MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2022-05-12 US disclosed
US-20190274334-A1 COMPOUNDS THAT MODULATE CALCIUM-SENSING RECEPTOR ACTIVITY FOR MODULATING KOKUMI TASTE AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2019-09-12 US disclosed
EP-2796546-B1 Incorporation of unnatural amino acids SCRIPPS RESEARCH INST (US) 2017-08-09 EP disclosed
EP-2796546-A1 In vivo incorporation of unnatural amino acids The Scripps Research Institute (US) 2014-10-29 EP disclosed
JP-H1156379-A PRODUCTION OF OPTICALLY ACTIVE COMPOUND KYOWA HAKKO KOGYO CO LTD 1999-03-02 JP disclosed
EP-0884390-A2 Method for producing an optically active compound KYOWA HAKKO KOGYO CO., LTD. (JP) 1998-12-16 EP disclosed
EP-0884390-A2 Method for producing an optically active compound KYOWA HAKKO KOGYO CO., LTD. (JP) 1998-12-16 EP disclosed
US-5643769-A Process for producing an optically active γ-hydroxy-L-glutamic acid KYOWA HAKKO KOGYO CO., LTD. (JP) 1997-07-01 US disclosed
US-5607848-A MIXING GLYOXYLIC ACID, PYRUVIC ACID, MICROORGANISM KYOWA HAKKO KOGYO CO., LTD. (JP) 1997-03-04 US disclosed
EP-0692539-A2 Process for producing an optically active gamma-hydroxy-L-glutamic acid KYOWA HAKKO KOGYO CO., LTD. (JP) 1996-01-17 EP disclosed
EP-0670371-A2 Process for producing optically active 4-hydroxy-2-ketoglutaric acids KYOWA HAKKO KOGYO CO., LTD. (JP) 1995-09-06 EP disclosed