Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.56 |
| ▸ | SLC1A1 | P43005 | 5/20 | 0.52 |
| ▸ | SLC1A3 | P43003 | 5/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 5/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.48 |
| ▸ | GRIK1 | P39086 | 4/20 | 0.46 |
| ▸ | GRIK2 | Q13002 | 4/20 | 0.46 |
| ▸ | GGT1 | P19440 | 2/20 | 0.46 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL393346 | 1.00 | SLC7A5 (0.56) | SLC7A5SLC1A1SLC1A3SLC1A2PTGS1 | |
| SCHEMBL4254400 | 1.00 | SLC7A5 (0.56) | SLC7A5SLC1A1SLC1A3SLC1A2PTGS1 | |
| SCHEMBL4947418 | 1.00 | SLC7A5 (0.56) | SLC7A5SLC1A1SLC1A3SLC1A2PTGS1 | |
| SCHEMBL5823952 | 1.00 | SLC7A5 (0.56) | SLC7A5SLC1A1SLC1A3SLC1A2PTGS1 | |
| SCHEMBL13746293 | 1.00 | SLC7A5 (0.56) | SLC7A5SLC1A1SLC1A3SLC1A2PTGS1 | |
| SCHEMBL196983 | 1.00 | SLC7A5 (0.56) | SLC7A5SLC1A1SLC1A3SLC1A2PTGS1 | |
| SCHEMBL1607862 | 1.00 | SLC7A5 (0.56) | SLC7A5SLC1A1SLC1A3SLC1A2PTGS1 | |
| SCHEMBL305904 | 1.00 | SLC7A5 (0.56) | SLC7A5SLC1A1SLC1A3SLC1A2PTGS1 | |
| SCHEMBL13753646 | 1.00 | SLC7A5 (0.56) | SLC7A5SLC1A1SLC1A3SLC1A2PTGS1 | |
| SCHEMBL3744052 | 0.84 | OR51E2 (0.42) | SLC7A5SLC1A1SLC1A3SLC1A2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220325035-A1 | POLYESTER, POLYESTERAMIDE, AND POLYAMIDE COMPOSITIONS | IYER ANANTH V (US) | 2022-10-13 | — | — | US | claimed |
| EP-0692539-B1 | Process for producing an optically active gamma-hydroxy-L-glutamic acid | KYOWA HAKKO KOGYO KK (JP) | 1999-09-22 | — | — | EP | claimed |
| US-5643769-A | Process for producing an optically active γ-hydroxy-L-glutamic acid | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-01 | — | — | US | claimed |
| EP-0692539-A2 | Process for producing an optically active gamma-hydroxy-L-glutamic acid | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-01-17 | — | — | EP | claimed |
| JP-11155572-A | — | — | None | — | — | JP | disclosed |
| US-20220325035-A1 | POLYESTER, POLYESTERAMIDE, AND POLYAMIDE COMPOSITIONS | IYER ANANTH V (US) | 2022-10-13 | — | — | US | disclosed |
| EP-0884390-B1 | Method for producing an optically active compound | KYOWA HAKKO KOGYO KK (JP) | 2006-05-10 | — | — | EP | disclosed |
| US-20020188022-A1 | Methods for modulation, stimulation, and inhibition of glutamate reuptake | ANNOVIS. INC. | 2002-12-12 | — | — | US | disclosed |
| US-20020115688-A1 | Screen for glutamate reuptake inhibitors, stimulators, and modulators | ANNOVIS, INC. | 2002-08-22 | — | — | US | disclosed |
| US-6365381-B2 | PRODUCING (S)-4-HYDROXY-2-KETOGLUTARIC ACID AND COMPOUNDS WHICH ARE FORMED BY BIOSYNTHESIS FROM THIS PRECURSOR USING RECOMBINANT MICROORGANISM CARRYING A RECOMBINANT DNA HARBORING THIS ACID ALDOLASE GENE, SUGAR AND GLYOXYLIC ACID | KYOWA HAKKO KOGYO, LTD. (JP) | 2002-04-02 | — | — | US | disclosed |
| US-20020006645-A1 | Method for producing optically active compound | HASHIMOTO SHIN-ICHI (JP) | 2002-01-17 | — | — | US | disclosed |
| US-6207427-B1 | ALLOWING RECOMBINANT MICROORGANISM CARRYING RECOMBINANT DNA HARBORING (S)-4-HYDROXY-2-KETOGLUTARIC ACID ALDOLASE GENE TO ACT ON SUGAR AND GLYOXYLIC ACID IN AN AQUEOUS MEDIUM, AND COLLECTING OPTICALLY ACTIVE (S)-4-HYDROXY-2-KETOGLUTARIC ACID | KYOWA HAKKO KOGYO, LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| EP-0692539-B1 | Process for producing an optically active gamma-hydroxy-L-glutamic acid | KYOWA HAKKO KOGYO KK (JP) | 1999-09-22 | — | — | EP | disclosed |
| JP-H11155572-A | 4(R)-HYDROXY-2-KETOGLUTARIC ACID ALDOLASE AND DNA CODING FOR THE ENZYME | KYOWA HAKKO KOGYO CO LTD | 1999-06-15 | — | — | JP | disclosed |
| EP-0884390-A2 | Method for producing an optically active compound | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-12-16 | — | — | EP | disclosed |
| US-5643769-A | Process for producing an optically active γ-hydroxy-L-glutamic acid | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-01 | — | — | US | disclosed |
| EP-0692539-A2 | Process for producing an optically active gamma-hydroxy-L-glutamic acid | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-01-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020188022-A1 | Methods for modulation, stimulation, and inhibition of glutamate reuptake | SLC1A2, SLC18A2, SLC1A1 | SLC7A5 80/4885SLC1A1 3/4885SLC1A3 6/4885 |
| US-20020115688-A1 | Screen for glutamate reuptake inhibitors, stimulators, and modulators | SLC18A2, SLC1A2, SLC1A1 | SLC7A5 56/4885SLC1A1 3/4885SLC1A3 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.