SCHEMBL1607862

SCHEMBL1607862

N[C@H](CC(O)C(=O)O)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.56
SLC1A1 P43005 5/20 0.52
SLC1A3 P43003 5/20 0.50
SLC1A2 P43004 5/20 0.50
PTGS1 P23219 1/20 0.48
SLC7A11 Q9UPY5 1/20 0.48
GRIK1 P39086 4/20 0.46
GRIK2 Q13002 4/20 0.46
GGT1 P19440 2/20 0.46
GRM1 Q13255 1/20 0.46
GRM2 Q14416 1/20 0.46
OR51E2 Q9H255 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL393346 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL4254400 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL4947418 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL5819946 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL5823952 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL13746293 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL196983 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL305904 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL13753646 1.00 SLC7A5 (0.56) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1
SCHEMBL3744052 0.84 OR51E2 (0.42) SLC7A5SLC1A1SLC1A3SLC1A2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4181781-B1 BREATH-BASED THERAPEUTIC DRUG MONITORING METHOD UNIV KINDERSPITAL BEIDER BASEL (CH) 2026-05-20 EP disclosed
EP-4541812-A2 GENERATION OF A HIGH PRODUCING RECOMBINANT CHINESE HAMSTER OVARY CELL LINE FOR THERAPEUTIC PROTEIN PRODUCTION Sanofi (FR) 2025-04-23 EP disclosed
EP-4214308-B1 GENERATION OF A HIGH PRODUCING RECOMBINANT CHINESE HAMSTER OVARY CELL LINE FOR THERAPEUTIC PROTEIN PRODUCTION SANOFI SA (FR) 2024-11-20 EP disclosed
EP-4419094-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS Edison Oncology (US) 2024-08-28 EP disclosed
US-20240043878-A1 GENERATION OF A HIGH PRODUCING RECOMBINANT CHINESE HAMSTER OVARY CELL LINE FOR THERAPEUTIC PROTEIN PRODUCTION SANOFI (FR) 2024-02-08 US disclosed
US-20230277125-A1 BREATH-BASED THERAPEUTIC DRUG MONITORING METHOD UNIVERSITÄTS-KINDERSPITAL BEIDER BASEL (CH) 2023-09-07 US disclosed
EP-4214308-A1 GENERATION OF A HIGH PRODUCING RECOMBINANT CHINESE HAMSTER OVARY CELL LINE FOR THERAPEUTIC PROTEIN PRODUCTION Sanofi (FR) 2023-07-26 EP disclosed
CN-116457468-A Production of high-yielding recombinant chinese hamster ovary cell lines for therapeutic protein production 赛诺菲 2023-07-18 CN disclosed
US-20230212549-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2023-07-06 US disclosed
US-20230212549-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF 3B PHARMACEUTICALS GMBH (DE) 2023-07-06 US disclosed
US-7811804-B2 synthetic or recombinant polypeptide having a nitrilase activity; have increased activity and stability at increased pH and temperature VERENIUM CORPORATION (US) 2010-10-12 US disclosed
US-20100086986-A1 Increased activity and stability at increased pH and temperature; making a chiral alpha -hydroxy acid molecule, a chiral amino acid molecule, a chiral beta -hydroxy acid molecule, or a chiral gamma-hydroxy acid molecule, from a molecule with a cyanohydrin moiety or an aminonitrile moiety VERENIUM CORPORATION (US) 2010-04-08 US disclosed
US-20100086986-A1 Increased activity and stability at increased pH and temperature; making a chiral alpha -hydroxy acid molecule, a chiral amino acid molecule, a chiral beta -hydroxy acid molecule, or a chiral gamma-hydroxy acid molecule, from a molecule with a cyanohydrin moiety or an aminonitrile moiety VERENIUM CORPORATION (US) 2010-04-08 US disclosed
US-7651849-B2 Increased activity and stability at increased pH and temperature VERENIUM CORPORATION 2010-01-26 US disclosed
US-7651849-B2 Increased activity and stability at increased pH and temperature VERENIUM CORPORATION 2010-01-26 US disclosed
US-20100009426-A1 synthetic or recombinant polypeptide having a nitrilase activity; have increased activity and stability at increased pH and temperature VERENIUM CORPORATION (US) 2010-01-14 US disclosed
US-20090176976-A1 Increased activity and stability at increased pH and temperature VERENIUM CORPORATION 2009-07-09 US disclosed
US-20090176976-A1 Increased activity and stability at increased pH and temperature VERENIUM CORPORATION 2009-07-09 US disclosed
US-7521216-B2 Nitrilases and methods for making and using them VERENIUM CORPORATION (US) 2009-04-21 US disclosed
EP-2039762-A2 Nitralases Verenium Corporation (US) 2009-03-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230212549-A1 COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF FIBP, FN1, TPX2 SLC7A5 3294/4885SLC1A1 3353/4885SLC1A3 3634/4885
US-20100086986-A1 Increased activity and stability at increased pH and temperature; making a chiral alpha -hydroxy acid molecule, a chiral amino acid molecule, a chiral beta -hydroxy acid molecule, or a chiral gamma-hydroxy acid molecule, from a molecule with a cyanohydrin moiety or an aminonitrile moiety ASPH, AHSA1, DNPH1 SLC7A5 837/4885SLC1A1 1223/4885SLC1A3 1415/4885
US-20240043878-A1 GENERATION OF A HIGH PRODUCING RECOMBINANT CHINESE HAMSTER OVARY CELL LINE FOR THERAPEUTIC PROTEIN PRODUCTION DHODH, GLUL, GLS2 SLC7A5 434/4885SLC1A1 956/4885SLC1A3 825/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.