Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3931969 | 0.88 | FAAH (0.79) | FAAHALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL3933728 | 0.88 | FAAH (0.79) | FAAHALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL3939496 | 0.88 | FAAH (0.78) | FAAHALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL3935806 | 0.88 | FAAH (0.78) | FAAHALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL3943803 | 0.87 | FAAH (0.77) | FAAHALDH1A1HTTMAPTLMNA | |
| SCHEMBL3930671 | 0.87 | FAAH (0.77) | FAAHALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL3934937 | 0.87 | FAAH (0.77) | FAAHALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL3933874 | 0.85 | FAAH (0.75) | FAAHALDH1A1HTTLMNAMAPK1 | |
| SCHEMBL3939171 | 0.85 | FAAH (0.77) | FAAHALDH1A1HTTMAPTLMNA | |
| SCHEMBL3933957 | 0.85 | FAAH (0.77) | FAAHALDH1A1HTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |