Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13840022 | 0.95 | S1PR1 (0.42) | IGF1RALOX15S1PR1MEN1KMT2A | |
| SCHEMBL394254 | 0.95 | S1PR1 (0.42) | IGF1RALOX15S1PR1MEN1KMT2A | |
| SCHEMBL14732709 | 0.94 | S1PR1 (0.41) | S1PR1MEN1KMT2ACYP4A11ALDH1A1 | |
| SCHEMBL14732530 | 0.91 | IGF1R (0.46) | IGF1RALOX15S1PR1ALDH1A1CYP1A2 | |
| SCHEMBL26295423 | 0.89 | IGF1R (0.46) | IGF1RALOX15MEN1KMT2ACYP4A11 | |
| SCHEMBL9495382 | 0.89 | IGF1R (0.46) | IGF1RALOX15MEN1KMT2ACYP4A11 | |
| SCHEMBL14732547 | 0.87 | CYP1A2 (0.41) | IGF1RALOX15S1PR1ALDH1A1CYP1A2 | |
| SCHEMBL14732526 | 0.87 | CYP1A2 (0.41) | IGF1RALOX15S1PR1ALDH1A1CYP1A2 | |
| SCHEMBL2312551 | 0.87 | S1PR1 (0.39) | IGF1RALOX15S1PR1CYP4A11ALDH1A1 | |
| SCHEMBL25445757 | 0.86 | LPL (0.44) | IGF1RALOX15ALDH1A1CYP3A4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101327-B2 | Charge transport and overcoating layers formed by combining a film forming polycarbonate binder and a hole transporting hydroxy triarylamine compound; surface energy-reducing silicone is crosslinked with heat or ultraviolet radiation and the coating is dried to remove solvent | XEROX CORPORATION (US) | 2012-01-24 | — | — | US | claimed |
| US-20080057424-A1 | Overcoat for electrophotographic imaging member and methods of making and using same | XEROX CORPORATION | 2008-03-06 | — | — | US | claimed |
| US-8101327-B2 | Charge transport and overcoating layers formed by combining a film forming polycarbonate binder and a hole transporting hydroxy triarylamine compound; surface energy-reducing silicone is crosslinked with heat or ultraviolet radiation and the coating is dried to remove solvent | XEROX CORPORATION (US) | 2012-01-24 | — | — | US | disclosed |
| US-20080057424-A1 | Overcoat for electrophotographic imaging member and methods of making and using same | XEROX CORPORATION | 2008-03-06 | — | — | US | disclosed |