SCHEMBL394254

SCHEMBL394254

Cc1ccc(N(c2ccc(CCCO)cc2)c2ccc(C)c(C)c2)cc1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S1PR1 P21453 1/20 0.42
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
CYP4A11 Q02928 3/20 0.39
ALDH1A1 P00352 1/20 0.39
CA2 P00918 2/20 0.38
CYP4F2 P78329 2/20 0.37
BCHE P06276 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CA1 P00915 1/20 0.36
PPARA Q07869 1/20 0.36
LPL P06858 4/20 0.35
LIPG Q9Y5X9 4/20 0.35
LTA4H P09960 1/20 0.35
EPHX2 P34913 1/20 0.35
TRPV1 Q8NER1 1/20 0.34
MGLL Q99685 1/20 0.34
SKP2 Q13309 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13840022 1.00 S1PR1 (0.42) S1PR1MEN1KMT2ACYP4A11ALDH1A1
SCHEMBL14732709 0.98 S1PR1 (0.41) S1PR1MEN1KMT2ACYP4A11ALDH1A1
SCHEMBL393385 0.95 IGF1R (0.41) S1PR1MEN1KMT2ACYP4A11ALDH1A1
SCHEMBL12039337 0.90 MEN1 (0.43) S1PR1MEN1KMT2ALTA4HEPHX2
SCHEMBL14371522 0.90 S1PR1 (0.44) S1PR1MEN1KMT2ACYP4A11ALDH1A1
SCHEMBL19018168 0.90 S1PR1 (0.44) S1PR1MEN1KMT2ACYP4A11ALDH1A1
SCHEMBL12593387 0.86 SKP2 (0.47) ALDH1A1CA2CYP3A4CYP2D6CYP2C9
SCHEMBL11887110 0.86 SKP2 (0.47) ALDH1A1CA2CYP3A4CYP2D6CYP2C9
SCHEMBL5061273 0.86 SKP2 (0.47) ALDH1A1CA2CYP3A4CYP2D6CYP2C9
SCHEMBL279458 0.86 RARB (0.38) S1PR1MEN1KMT2ACYP4A11ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9034544-B2 Compound, charge transporting film, photoelectric conversion device, and electrophotographic photoreceptor using the compound, method of producing electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-05-19 US disclosed
US-9034544-B2 Compound, charge transporting film, photoelectric conversion device, and electrophotographic photoreceptor using the compound, method of producing electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-05-19 US disclosed
US-8475982-B2 Charge-transporting compound, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2013-07-02 US disclosed
US-8475982-B2 Charge-transporting compound, electrophotographic photoreceptor, image-forming apparatus, and process cartridge FUJI XEROX CO., LTD. (JP) 2013-07-02 US disclosed
US-20130052572-A1 COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE COMPOUND, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed
US-20130052572-A1 COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE COMPOUND, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed
US-8101327-B2 Charge transport and overcoating layers formed by combining a film forming polycarbonate binder and a hole transporting hydroxy triarylamine compound; surface energy-reducing silicone is crosslinked with heat or ultraviolet radiation and the coating is dried to remove solvent XEROX CORPORATION (US) 2012-01-24 US disclosed
US-20080057424-A1 Overcoat for electrophotographic imaging member and methods of making and using same XEROX CORPORATION 2008-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130052572-A1 COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE COMPOUND, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS PDE6C, SLC9A2, SCNN1G S1PR1 3032/4885MEN1 1093/4885KMT2A 1603/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.